Results 81 to 90 of about 3,184,218 (349)

RECIPROCAL TRANSLOCATIONS AND TRANSLOCATION DISOMICS OF ASPERGILLUS AND THEIR USE FOR GENETIC MAPPING

Genetics, 1975
ABSTRACT Two new techniques are described for genetic mapping of reciprocal translocations in A. nidulans, which can be used to locate centromeres and meiotically unlinked markers. They both make use of unbalanced disomics from heterozygous translocation crosses. These are mainly hyperhaploids of two classes: either typical-looking n + 1
openaire   +3 more sources

Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.

Cancer Research, 2018
Translocations of retinoic acid receptor-α (RARA), typically PML-RARA, are a genetic hallmark of acute promyelocytic leukemia (APL). However, because a small fraction of APL lack translocations of RARA, we focused here on APL cases without RARA ...
T. Osumi, Shinichi Tsujimoto, Moe Tamura, Meri Uchiyama, K. Nakabayashi, K. Okamura, Masanori Yoshida, D. Tomizawa, A. Watanabe, Hiroyuki Takahashi, T. Hori, Shohei Yamamoto, K. Hamamoto, M. Migita, Hiroko Ogata-Kawata, T. Uchiyama, Hiroe Kizawa, Hitomi Ueno-Yokohata, Ryota Shirai, M. Seki, K. Ohki, J. Takita, T. Inukai, S. Ogawa, T. Kitamura, Kimikazu Matsumoto, K. Hata, N. Kiyokawa, S. Goyama, Motohiro Kato   +29 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

The Potential of Lr19 and Bdv2 Translocations to Improve Yield and Disease Resistance in the High Rainfall Wheat Zones of Australia

Agronomy, 2015
Chromosomal translocations in wheat derived from alien species are a valuable source of genetic diversity that have provided increases in resistance to various diseases and improved tolerance to abiotic stresses in wheat. These alien genomic segments can
Garry Rosewarne, David Bonnett, Greg Rebetzke, Paul Lonergan, Philip J. Larkin   +4 more
doaj   +1 more source

Reassessment of the evolution of wheat chromosomes 4A, 5A, and 7B. [PDF]

, 2018
Key messageComparison of genome sequences of wild emmer wheat and Aegilops tauschii suggests a novel scenario of the evolution of rearranged wheat chromosomes 4A, 5A, and 7B.
Deal, Karin R, Devos, Katrien M, Distelfeld, Assaf, Dvorak, Jan, Gill, Bikram S, Gu, Yong Q, Jorgensen, Chad M, Luo, Ming-Cheng, McGuire, Patrick E, Qi, Peng, Wang, Le, Zhu, Tingting   +11 more
core  

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas.

Blood, 2016
Diffuse large B-cell lymphoma (DLBCL) is one of the most common and aggressive types of B-cell lymphoma. Deregulation of proto-oncogene expression after a translocation, most notably to the immunoglobulin heavy-chain locus (IGH), is one of the hallmarks ...
Konstantinos Georgiou, Longyun Chen, M. Berglund, W. Ren, N. F. de Miranda, Susana Lisboa, Marco Fangazio, Shida Zhu, Yong Hou, Kui Wu, W. Fang, Xianhuo Wang, B. Meng, Li Zhang, Yixin Zeng, G. Bhagat, M. Nordenskjöld, C. Sundström, G. Enblad, R. Dalla-Favera, Huilai Zhang, M. Teixeira, L. Pasqualucci, Roujun Peng, Q. Pan-Hammarström   +24 more
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

The importance of genetic diversity for the translocation of eight threatened plant species into the wild

Global Ecology and Conservation, 2020
Considering ongoing biodiversity losses, translocations of threatened plant species into the wild has become a common conservation technique although they are considered laborious, expensive and rarely successful.
Deborah Schäfer, Hugo Vincent, Markus Fischer, Anne Kempel   +3 more
doaj  

Protein import into the endosymbiotic organelles of apicomplexan parasites [PDF]

, 2018
The organelles of endosymbiotic origin, plastids, and mitochondria, evolved through the serial acquisition of endosymbionts by a host cell. These events were accompanied by gene transfer from the symbionts to the host, resulting in most of the organellar
Fellows, Justin, Johnson, Carla, Mallo, Natalia, Sheiner, Lilach   +3 more
core   +1 more source

Genome‐wide association study discovered genetic variation and candidate genes of fibre quality traits in Gossypium hirsutum L.

Plant Biotechnology Journal, 2017
Summary Genetic improvement of fibre quality is one of the main breeding goals for the upland cotton, Gossypium hirsutum, but there are difficulties with precise selection of traits.
Zhengwen Sun, Xingfen Wang, Zhengwen Liu, Qishen Gu, Yan Zhang, Zhikun Li, H. Ke, Jun Yang, Jinhua Wu, Liqiang Wu, Guiyin Zhang, Caiying Zhang, Zhiying Ma   +12 more
semanticscholar   +1 more source