Results 81 to 90 of about 2,347,193 (305)

Translocation and Aquaculture Impact on Genetic Diversity and Composition of Wild Self-Sustainable Ostrea edulis Populations in the Adriatic Sea

Frontiers in Marine Science, 2020
The European flat oyster, Ostrea edulis, is a keystone species suffering major population declines due to overfishing, habitat loss and parasite diseases.
Tanja Šegvić-Bubić, Iva Žužul, Igor Talijančić, Nika Ugrin, Ivana Lepen Pleić, Luka Žuvić, Nika Stagličić, Leon Grubišić   +7 more
doaj   +1 more source

Assembly and mechanism of bacterial twin-arginine translocation systems [PDF]

The bacterial twin-arginine translocation (Tat) pathway is able to export pre-folded cofactor containing proteins across the cytoplasmic membrane. Tat substrates bear cleavable N-terminal signal peptides that are characterized by the presence of a ...
Baglieri, J.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Preprotein recognition and translocation by the Toc complex [PDF]

, 2005
Preproptein recognition and translocation across the outer envelope membrane of plastids is catalysed by a proteinaceous machinery, called Toc translocon.
Becker, Thomas
core   +1 more source

Conservation units and the origin of planted individuals of an endangered endemic species Lobelia boninensis in the Ogasawara Islands

Scientific Reports
The Ogasawara Islands, one of the UNESCO World Natural Heritage Site located about 1000 km south of Japan’s main island, harbor numerous endemic species, many of which are as endangered.
Chikashi Hata, Chiharu Endo, Hiroshi Tanaka, Miho Hiruma, Maiko Kumamoto, Izumi Takenaka, Takashi Makino, Kento Niinaka, Yoshihisa Suyama, Shun K. Hirota, Michimasa Yamasaki, Yuji Isagi   +11 more
doaj   +1 more source

Evaluation of translocation as a tool for mitigating development threats to great crested newts (Triturus cristatus) in England, 1990-2001 [PDF]

, 2004
Great crested newts (Triturus cristatus) are protected under European and UK legislation, but are frequently the subject of conflict between development and conservation in England.
Paul W. Edgar, Jim P. Foster, Foster, Jim P., Richard A. Griffiths, Edgar, Paul W., Griffiths, Richard A.   +5 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Acute myeloid leukemia with translocation: A case report and review of the literature

SAGE Open Medical Case Reports, 2018
Chromosomal rearrangement involving the KMT2A gene is one of the most common genetic alteration in acute myeloid leukemia. A total of 135 different KMT2A rearrangements have been identified, where 94 translocation partner genes are now characterized at ...
Shaimaa Elzamly, Santosh Chavali, Vijay Tonk, Sahil Tonk, Sumit Gaur, Darlene Tarango, Alireza Torabi   +6 more
doaj   +1 more source

Mechanism of Sec61-mediated insertion of proteins into the endoplasmic reticulum membrane [PDF]

, 2010
In eukaryotic cells, hydrophobic signal sequences of newly synthesized secretory and membrane proteins target them to the Sec61 translocon in the endoplasmic reticulum (ER) membrane.
Kocik, Lucyna
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source