Results 91 to 100 of about 999,565 (340)

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

Predation impedes recovery of Sierra Nevada bighorn sheep

California Fish and Wildlife Journal, 2021
Translocation of animals into formerly occupied habitat is a key element of the recovery plan for Sierra Nevada bighorn sheep (Ovis canadensis sierrae), which are state (California) and federally listed as endangered. However, implementing Sierra bighorn
Daniel J. Gammons, Jeffrey L. Davis, David W. German, Kristin Denryter, John D. Wehausen, Thomas R. Stephenson   +5 more
doaj   +1 more source

Electrophoresis of a polyelectrolyte through a nanopore [PDF]

, 2006
A hydrodynamic model for determining the electrophoretic speed of a polyelectrolyte through a nanopore is presented. It is assumed that the speed is determined by a balance of electrical and viscous forces arising from within the pore and that classical ...
E. Lauga, F. Morrison, Jr., F. Oosawa, G. Batchelor, H. Helmholtz, M. Smoluchowski, S. Ghosal, Sandip Ghosal, W. Russel   +8 more
core   +2 more sources

Telomeres and Chromosomal Translocations [PDF]

, 2018
Chromosomal translocations are now well understood to not only constitute signature molecular markers for certain human cancers but often also to be causative in the genesis of that tumor. Despite the obvious importance of such events, the molecular mechanism of chromosomal translocations in human cells remains poorly understood.
Duncan M. Baird, Eric A. Hendrickson
openaire   +3 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Integrative biochar and melatonin application mitigates lead toxicity in rice by modulating antioxidant activities and iron plaque formation and downregulating the expression of metal uptake genes

Frontiers in Plant Science
Lead (Pb) is a common toxic metal that causes severe health and environmental problems. However, the defensive role and underlying mechanism of combined biochar (BC) and melatonin (MT) against Pb stress are still unclear.
Tahir Abbas Khan, Qitao Su, Huang Guoqin, Zhixuan Du, Zhixuan Du, Mehmood Ali Noor, Tahani A. Y. Asseri, Muhammad Umair Hassan   +7 more
doaj   +1 more source

11C-PET imaging reveals transport dynamics and sectorial plasticity of oak phloem after girdling

Frontiers in Plant Science, 2013
Carbon transport processes in plants can be followed non-invasively by repeated application of the short-lived positron-emitting radioisotope 11C, a technique which has rarely been used with trees. Recently, positron emission tomography (PET) allowing 3D
Veerle eDe Schepper, Jonas eBühler, Michael eThorpe, Michael eThorpe, Michael eThorpe, Gerhard eRoeb, Gregor eHuber, Dagmar evan Dusschoten, Siegfried eJahnke, Kathy eSteppe   +9 more
doaj   +1 more source

Directed motion emerging from two coupled random processes: Translocation of a chain through a membrane nanopore driven by binding proteins

, 2005
We investigate the translocation of a stiff polymer consisting of M monomers through a nanopore in a membrane, in the presence of binding particles (chaperones) that bind onto the polymer, and partially prevent backsliding of the polymer through the pore.
Alberts B, Ambjörnsson T, Ambjörnsson T, Bates M, Chauwin J-F, Elston T C, Elston T C, Farkas Z, Gardiner C W, Gerland U, Harada Y, Lubensky D K, McQuistan R B, Meller A, Metzler R, Metzler R, Michael A Lomholt, Peskin C S, Press W H, Ralf Metzler, Risken H, Simon S F, Tobias Ambjörnsson, van Kampen N G   +23 more
core   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Evaluation of Antimicrobial Interventions against E. coli O157:H7 on the Surface of Raw Beef to Reduce Bacterial Translocation during Blade Tenderization

Foods, 2019
The US Department of Agriculture, Food Safety Inspection Service (USDA-FSIS) considers mechanically-tenderized beef as “non-intact„ and a food safety concern because of the potential for translocation of surface Escherichia coli O157:H7 into ...
Peter M. Muriana, Jackie Eager, Brent Wellings, Brad Morgan, Jacob Nelson, Kalpana Kushwaha   +5 more
doaj   +1 more source