Results 91 to 100 of about 1,246,248 (385)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome

open access: yeseLife, 2016
Internal ribosome entry sites (IRESs) mediate cap-independent translation of viral mRNAs. Using electron cryo-microscopy of a single specimen, we present five ribosome structures formed with the Taura syndrome virus IRES and translocase eEF2•GTP bound ...
Priyanka D Abeyrathne   +4 more
doaj   +1 more source

Translocation of structured polynucleotides through nanopores

open access: yes, 2004
We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired regions within the molecules presents significant kinetic barriers for the ...
Akeson M   +20 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

GENOTYPIC VARIATION IN ZINC EFFICIENCY (ZE) OF WHEAT GENOTYPES UNDER CULTURE SOLUTION AND FIELD CONDITIONS

open access: yesPakistan Journal of Agriculture, Agricultural Engineering & Veterinary Sciences, 2017
An experiment was executed to assess the relative zinc (Zn) efficiencies of advanced wheat lines in chelate-buffered hydroponic culture solutions and field conditions.
M. Imtiaz, P. Khan, A. Raza, W. Mohammad
doaj  

Plasmodesmos: transporte simplástico de herbicidas na planta Plasmodesmata: symplastic transport of herbicides within the plant

open access: yesPlanta Daninha, 2007
Plasmodesmos são canais responsáveis pela conexão citoplasmática entre células vizinhas, possibilitando a troca de moléculas de informação, funcionais, estruturais ou ainda de xenobióticos entre as células pertencentes a um mesmo grupo.
G. Concenço   +3 more
doaj   +1 more source

Exact steady-state velocity of ratchets driven by random sequential adsorption

open access: yes, 2008
We solve the problem of discrete translocation of a polymer through a pore, driven by the irreversible, random sequential adsorption of particles on one side of the pore.
Ambjörnsson T   +11 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Survival of translocated Columbian Sharp-tailed Grouse: recognizing trends in post-release mortality to improve reintroductions

open access: yesAvian Conservation and Ecology, 2022
Survival of translocated prairie-grouse (Tympanuchus spp.) is often low in the first few weeks or months following release into a novel environment. Understanding the processes and mechanisms that influence short-term, post-release survival, such as ...
Steven Roy. Mathews   +4 more
doaj  

Translocation arrest by reversible folding of a precursor protein imported into mitochondria [PDF]

open access: yes, 1989
Passage of precursor proteins through translocation contact sites of mitochondria was investigated by studying the import of a fusion protein consisting of the NH2-terminal 167 amino acids of yeast cytochrome b2 precursor and the complete mouse ...
Guiard, Bernard   +5 more
core  

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