Results 81 to 90 of about 698,201 (312)
Evolutionary ApplicationsHabitat loss and fragmentation are major drivers of biodiversity decline, reducing connectivity among populations and leading to genetic isolation, loss of diversity, increased inbreeding, and reduced fitness.
Debra M. Shier +7 more
doaj +1 more source
Chromosome territory formation attenuates the translocation potential of cells
eLife, 2019 The formation and spatial arrangement of chromosome territories (CTs) in interphase has been posited to influence the outcome and frequency of genomic translocations.
Leah F Rosin +5 more
doaj +1 more source
The Process of Microbial Translocation
Annals of Surgery, 1990 The process of microbial translocation was studied using Candida albicans, Escherichia coli, or endotoxin instilled into Thiry-Vella loops of thermally injured guinea pigs and rats. Translocation of C. albicans occurred by direct penetration of enterocytes by a unique process different from classical phagocytosis.
Alexander, J +8 more
openaire +4 more sources
, 2009 The disrupted-in-schizophrenia 1 (DISC1) gene is a candidate gene in schizophrenia. The balanced t(1;11)(q42.1;q14.3) translocation with a breakpoint between exons 8 and 9 of DISC1 has been found to be co- segregated with psychosis in a Scottish family ...
劉玉麗;劉智民;田蕙芬;胡海國 +1 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome
eLife, 2016 Internal ribosome entry sites (IRESs) mediate cap-independent translation of viral mRNAs. Using electron cryo-microscopy of a single specimen, we present five ribosome structures formed with the Taura syndrome virus IRES and translocase eEF2•GTP bound ...
Priyanka D Abeyrathne +4 more
doaj +1 more source
Stereoselective Radical Translocations
CHIMIA, 2008 The stereochemical outcome of intramolecular radical mediated hydrogen transfer (= radical translocation) is discussed. Low to excellent levels of stereocontrol are observed making such processes attractive for applications in target-oriented synthesis.
Renaud, Philippe +5 more
openaire +6 more sources
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Planta Daninha, 2007 Plasmodesmos são canais responsáveis pela conexão citoplasmática entre células vizinhas, possibilitando a troca de moléculas de informação, funcionais, estruturais ou ainda de xenobióticos entre as células pertencentes a um mesmo grupo.
G. Concenço +3 more
doaj +1 more source
Helicobacter pylori type IV secretion apparatus exploits beta1 integrin in a novel RGD-independent manner. [PDF]
, 2009 Translocation of the Helicobacter pylori (Hp) cytotoxin-associated gene A (CagA) effector protein via the cag-Type IV Secretion System (T4SS) into host cells is a major risk factor for severe gastric diseases, including gastric cancer.
Haas, Rainer +42 more
core +2 more sources