Results 241 to 250 of about 1,195,157 (388)

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

Intestinal bacteria translocation promotes β-cell dysfunction in DIO mice. [PDF]

Sci Rep
Yu XF, Gurung C, Yu Z, Xiao W, Kerem G, Teng B, Zhang JV, Su Z, Zhou Y, Ren PG.   +9 more
europepmc   +1 more source

SPECIALIZED "TRANSFER CELLS" IN MINOR VEINS OF LEAVES AND THEIR POSSIBLE SIGNIFICANCE IN PHLOEM TRANSLOCATION [PDF]

, 1968
B. E. S. Gunning, J. S. Pate, L. G. Briarty   +2 more
openalex   +1 more source

SWEETs, transporters for intracellular and intercellular sugar translocation.

Current opinion in plant biology, 2015
J. Eom, Li-Qing Chen, Davide Sosso, Benjamin T. Julius, IW Lin, Xiao-Qing Qu, D. Braun, Wolf B. Frommer, Steven M Smith, S. Zeeman   +9 more
semanticscholar   +1 more source

At the Pointy End of Mechanobiology: AFM for Transient Biomechanical Analysis

Advanced Healthcare Materials, EarlyView.
Stem cell mechanosensitivity governs lineage commitment through mechanotransduction, but capturing these transient changes in living cells remains challenging. Advanced atomic force microscopy enables high‐resolution analysis of mechanical properties, real‐time protein distribution, and gene expression, offering fresh insights into cell‐environment ...
Kaiwen Zhang, Chayla L. Reeves, Mehrnoosh Moghaddar, Kate E. Fox, Aaron Elbourne, Amy Gelmi   +5 more
wiley   +1 more source

Aminoglycoside induces RIPOR2 translocation and phosphatidylserine externalization via distinct mechanisms. [PDF]

Front Cell Neurosci
Li J, Yang M, Zhao B.
europepmc   +1 more source

Autoradiographic method for studying absorption and translocation of herbicides using C¹⁴-labeled compounds

, 1958
Shigeki Yamaguchi, A. S. Crafts
openalex   +2 more sources

Metabolism of organophosphorus insecticides: IV. Translocation and metabolism of 32P-labelled Dipterex in cotton plant [PDF]

, 1965
I. Y. Mostafa, A. Hassan, S. M. A. D. Zayed   +2 more
openalex   +1 more source

Disruption of two novel genes by a translocation co-segregating with schizophrenia.

Human Molecular Genetics, 2000
J. Millar, Julie C. Wilson-Annan, S. Anderson, S. Christie, Martin S. Taylor, C. Semple, R. S. Devon, D. Clair, W. Muir, D. Blackwood, D. Porteous   +10 more
semanticscholar   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source