Results 251 to 260 of about 698,201 (312)

The Involvement of the Small GTPase Rac1 in Insulin Signaling That Regulates Plasma Membrane Translocation of the Fatty Acid Transporter CD36 in Mouse White Adipocytes. [PDF]

Int J Mol Sci
Takenaka N, Sakata M, Abe Y, Iha K, Satoh T.   +4 more
europepmc   +1 more source

Translocation [PDF]

, 2019
openaire   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

Advanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong, Wenlong Chen, Fanglong Liu, Shengyi Zhou, Bolin Yu, Yuying Wang, Xiqian Zhou, Xuehui Wang, Diya Liu, Zhuoyu Zhang, Xinran Wang, Mounia Lalouly, Yiwen Li, Zhefei Du, Tao Yan, Zhihui Xiao, Zhou Zhou, Huanhuan Zhu, Fengyuan Qian, Bowen Zheng, Lin Fang   +20 more
wiley   +1 more source

When recreational infrastructure contributes to endangered species conservation: genetic evaluation of translocated Primula vulgaris (Primulaceae) populations in a golf course area. [PDF]

Ann Bot
Triest L, Van Rossum F.
europepmc   +1 more source

Computation‐Guided Tunnel Engineering Enhances O2 Transport and H2O2 Resistance of Fe(II)/α‐Ketoglutarate‐Dependent Dioxygenases

Advanced Science, EarlyView.
This study presents a computational tunnel engineering strategy in Fe(II)/α‐ketoglutarate‐dependent dioxygenases (αKGDs) to enhance oxygen (O2) transport, an essential molecule for αKGDs, and limit hydrogen peroxide (H2O2) entry, an inhibitor from the αKG supply system.
Huan Liu, Lunjie Wu, Liying Mao, Songyin Zhao, Hu Liu, Shiyi Xin, Donglin Zhao, Jie Gu, Yan Xu, Xinye Wang, Yao Nie   +10 more
wiley   +1 more source

Nanopore-Based Protein Deceleration and Sensing Using Graphene/Si₃N₄ Dual Membrane Cavity. [PDF]

Adv Sci (Weinh)
Cao Y, He J, Si W.
europepmc   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

LIPUS combined with mild hyperthermia promotes rotator cuff healing via TRPV1/Ca²⁺/CaMKII-driven BACH2 nuclear translocation and inhibition of M1 polarization. [PDF]

J Orthop Translat
Xue X, Lin X, Gao A, Kuati A, Fu H, Cui G, Xu B, Song Q.   +7 more
europepmc   +1 more source

Iterative genetic testing identifies <i>SAMHD1</i> deficiency caused by a homozygous balanced translocation. [PDF]

J Hum Immun
Baker PJ, Zhang Y, Bishop I, Cleveland ML, McAllan AL, Hollway GE, Vedururu R, Kumar A, Krishnaswamy R, Wan KL, Kaub PA, Brown EL, Narayanan DL, Deveson IW, CIRCA, AADRY, Gowdie P, Renton WD, Ojaimi S, Fennell AP, Masters SL.   +20 more
europepmc   +1 more source