Results 51 to 60 of about 513,979 (295)
Driven polymer translocation through nanopores: slow versus fast dynamics
, 2009 We investigate the dynamics of polymer translocation through nanopores under external driving by 3D Langevin Dynamics simulations, focusing on the scaling of the average translocation time $\tau$ versus the length of the polymer, $\tau\sim N^{\alpha ...
Ala-Nissila, Tapio +3 more
core +1 more source
On the Lubensky-Nelson model of polymer translocation through nanopores [PDF]
, 2012 We revisit the one-dimensional stochastic model of Lubensky and Nelson [Biophys. J 77, 1824 (1999)] for the electrically driven translocation of polynucleotides through alpha-hemolysin pores.
Akeson +46 more
core +2 more sources
Science, 2013 Structures of translocation intermediates reveal how transfer RNA molecules move through the ribosome during protein synthesis. [Also see Research Articles by Tourigny et al. , Zhou et al.
openaire +3 more sources
Proton translocation by transhydrogenase [PDF]
FEBS Letters, 2003 Transhydrogenase, in animal mitochondria and bacteria, couples hydride transfer between NADH and NADP+ to proton translocation across a membrane. Within the protein, the redox reaction occurs at some distance from the proton translocation pathway and coupling is achieved through conformational changes.
openaire +4 more sources
Chaperone-assisted translocation [PDF]
Physical Biology, 2004 24 pages, 3 figures, LaTeX (IOP class file)
Ambjørnsson, T, Metzler, R
openaire +4 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Polymer Translocation in Crowded Environments
, 2007 We study the effect of the crowded nature of the cellular cytoplasm on the translocation of a polymer through a pore in a membrane. By systematically treating the entropic penalty due to crowding, we show that the translocation dynamics are significantly
A. P. Minton +8 more
core +1 more source
Fluctuations in polymer translocation [PDF]
Journal of Statistical Mechanics: Theory and Experiment, 2010 20 pages, 6 ...
Krapivsky, P., Mallick, K.
openaire +5 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source