Results 61 to 70 of about 513,979 (295)
Numerical simulation of conformational variability in biopolymer translocation through wide nanopores [PDF]
, 2009 Numerical results on the translocation of long biopolymers through mid-sized and wide pores are presented. The simulations are based on a novel methodology which couples molecular motion to a mesoscopic fluid solvent. Thousands of events of long polymers
Efthimios Kaxiras +5 more
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Evaluation of Potential Translocation Sites for an Imperiled Cyprinid, the Hornyhead Chub [PDF]
, 2018 Translocation of isolated species into suitable habitats may help to secure vulnerable, geographically limited species. Due to the decline of Wyoming Hornyhead Chub Nocomis biguttatus, conservation actions, such as the translocation of populations within
Hickerson, Brian T., Walters, Annika W.
core +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Translocation of a Polymer through a Nanopore across a Viscosity Gradient
, 2012 The translocation of a polymer through a pore in a membrane separating fluids of different viscosities is studied via several computational approaches.
de Haan, Hendrick W., Slater, Gary W.
core +1 more source
Frontiers in Microbiology, 2020 Chromosomal rearrangements (CR) such as translocations, duplications and inversions play a decisive role in the adaptation of microorganisms to specific environments. In enological Saccharomyces cerevisiae strains, CR involving the promoter region of the
Philippe Marullo +13 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The gateway to chloroplast: re-defining the function of chloroplast receptor proteins [PDF]
, 2012 Chloroplast biogenesis often requires a tight orchestration between gene expression (both plastidial and nuclear) and translocation of similar to 3000 nuclear-encoded proteins into the organelle.
Bölter, Bettina +2 more
core +1 more source
Association of Down syndrome with major congenital anomalies in the North Indian population
Journal of Mahatma Gandhi Institute of Medical Sciences, 2021 Context: Down syndrome (DS), which usually occurs due to an extra chromosome 21 or a partial trisomy, is the most common genetic cause of intellectual disability.
Kanchan Bisht +4 more
doaj +1 more source