Results 161 to 170 of about 51,233 (262)

Can We Generalize About the Mortality Features of the 1918‐19 Influenza Pandemic? An Examination of a Small‐Scale and Isolated British Columbian Population

American Journal of Human Biology, Volume 38, Issue 6, June 2026.
ABSTRACT Objectives In this paper we use the small‐scale population of the Fort George area (located in the central interior of British Columbia, Canada) to test the applicability of the three signature mortality features of the 1918/19 influenza pandemic: mortality rates higher than those in preceding influenza epidemics except for the elderly ...
Lianne Tripp, Rhys Barber, Charlotte Boorman   +2 more
wiley   +1 more source

Brain regional susceptibility to tauopathy in individuals at risk for chronic traumatic encephalopathy

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION Chronic traumatic encephalopathy (CTE) is a tauopathy linked to repetitive head impacts. Factors influencing brain regional susceptibility to tau deposition and spreading remain unclear. METHODS We used three datasets: [18F]flortaucipir positron emission tomography (PET) in 157 former professional American football players and 53 ...
Tim L. T. Wiegand, Anna Rubinski, Leonard B. Jung, Nicolai Franzmeier, Hector Arciniega, Parsa Ravanfar, Anna Dewenter, Michael L. Alosco, Yorghos Tripodis, Yi Su, Hillary Protas, Alexander P. Lin, Ofer Pasternak, Kewei Chen, Michael J. Coleman, Sylvain Bouix, Charles H. Adler, Laura J. Balcer, Charles Bernick, Jeffrey L. Cummings, Robert A. Stern, Eric M. Reiman, Martha E. Shenton, Michael Ewers, Inga K. Koerte, for the DIAGNOSE CTE Research Project   +25 more
wiley   +1 more source

Identifying the optimal rapid antigen test for screening and determining the end of isolation: A modeling study. [PDF]

PLoS Comput Biol
Jeong YD, Hart WS, Ishikane M, Kim KS, Byun JH, Jung IH, Harrison MT, Aihara K, Ohmagari N, Brooke CB, Ke R, Thompson RN, Iwami S.   +12 more
europepmc   +1 more source

Hepatocyte growth factor/c‐Met signaling axis in human diseases: Mechanistic insights and therapeutic potential

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun, Hao Shu, Qian Zhang, Jishan Zheng, Yunyan Ma, Dengwang Chen, Jidong Zhang, Tao Song   +7 more
wiley   +1 more source

A narrative review of SARS-CoV-2 variants and long COVID. [PDF]

J Thorac Dis
Chai X, Qi H, Liu X, Zhou F, Jiang Y, Wu M, Lian S, Wang L, Bao Y.   +8 more
europepmc   +1 more source

The <i>R</i> = 1 threshold can misclassify epidemic stability. [PDF]

Commun Phys
Parag KV, Santillana M, Cori A, Obolski U.   +3 more
europepmc   +1 more source

Exacerbated Hepatic Stress and Systemic Metabolic Disruption Driven by SARS‐CoV‐2 P.1 Variant in K18‐hACE2 Mice

Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Introduction While severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been extensively studied in the context of pulmonary disease, its impact on metabolic organs remains poorly understood, particularly across experimental models.
Monara Kaélle Sérvulo Cruz Angelim, Patrícia Brito Rodrigues, Antônio Thiago Pereira Campos, Giovanni Freitas Gome, Gabriela Fabiano Souza, Valquíria Aparecida Matheus, Carlos Lenz Cesar, José Luiz Proença‐Módena, Marco Aurélio R. Vinolo, Pedro M. Moraes‐Vieira   +9 more
wiley   +1 more source

Measuring real-time disease transmissibility with temperature-dependent generation intervals. [PDF]

PLoS Comput Biol
Choo ELW, Parag KV, Chow JY, Lim JT.
europepmc   +1 more source

Adverse outcomes among pregnant women with COVID‐19 according to hospitalization status: A prospective individual participant data meta‐analysis in Europe and North America

International Journal of Gynecology &Obstetrics, Volume 173, Issue 3, Page 1197-1206, June 2026.
Abstract Background Understanding the varied impact of COVID‐19 severity on pregnancy outcomes is crucial for informed clinical management and targeted interventions. Objective To evaluate the impact of COVID‐19 on pregnancy outcomes, distinguishing between pregnant women managed in primary care and those requiring hospitalization.
Odette de Bruin, Emeline Maisonneuve, Eimir Hurley, Hedvig M. E. Nordeng, Anick Bérard, Odile Sheehy, Padma Kaul, Mayura U. Shinde, Austin Cosgrove, Jennifer G. Lyons, Elizabeth Messenger‐Jones, Maria E. Kempner, Sengwee Toh, Wei Hua, José J. Hernández‐Muñoz, Leyla Sahin, Carolyn E. Cesta, David Hägg, Rosa Gini, Olga Paoletti, Beatriz Poblador‐Plou, Sue Jordan, Clara L. Rodríguez‐Bernal, Francisco Sánchez‐Sáez, Régis Lassalle, Marie‐Agnès Bernard, Fariba Ahmadizar, Guillaume Favre, Alice Panchaud, Kitty W. M. Bloemenkamp, Kelly Plueschke, Corinne de Vries, Satu J. Siiskonen, Miriam C. J. M. Sturkenboom, on behalf of the CONSIGN Collaboration Group, Benjamin P. Geisler, Mark Walker, Steven Hawken, Sasha Bernatsky, Sherif Eltonsy, Emma Hoffman, Andrew B. Petrone, Jolene Mosley, Jenice Ko, Claudia Bartolini, Giuseppe Roberto, Giorgio Limoncella, Anna Girardi, Giulia Hyeraci, Antonio Gimeno‐Miguel, Jonás Carmona‐Pírez, Antonio Poncel‐Falcó, Aida Moreno‐Juste, Alexandra Prados‐Torres, Daniel Thayer, Ian Farr, Saira Ahmed, Ieuan Scanlon, Gabriel Sanfélix‐Gimeno, Isabel Hurtado, Anibal Garcia‐Sempere, Salvador Peiro, Jérémy Jové, Dunia Sakr, Cécile Droz‐Perroteau, Ema Alsina, David Baud, Hilde M. Engjom, Judit Riera‐Arnau, Mònica Sabaté Gallego, Elena Ballarín Alins, Cristina Aguilera Martin, Melissa Kampman, Celline Brasil   +73 more
wiley   +1 more source

The Effect of Protein Tagging on Aggregation and Phase Separation

Journal of Cellular Biochemistry, Volume 127, Issue 6, June 2026.
ABSTRACT Protein tags are widely used for purification, solubilization, detection, and imaging, yet they can substantially alter protein self‐assembly. This interference is particularly significant for intrinsically disordered proteins and low‐complexity domains, whose aggregation and phase separation are mediated by weak multivalent interactions that ...
Harunobu Saito, Kenji Sugase
wiley   +1 more source