Results 61 to 70 of about 5,841,576 (327)

Sugar Lego: gene composition of bacterial carbohydrate metabolism genomic loci

open access: yesBiology Direct, 2017
Background Bacterial carbohydrate metabolism is extremely diverse, since carbohydrates serve as a major energy source and are involved in a variety of cellular processes.
Anna Kaznadzey   +2 more
doaj   +1 more source

Electron transport properties of sub-3-nm diameter copper nanowires [PDF]

open access: yes, 2015
Density functional theory and density functional tight-binding are applied to model electron transport in copper nanowires of approximately 1 nm and 3 nm diameters with varying crystal orientation and surface termination. The copper nanowires studied are
Clarke, James S.   +6 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Trans2express – de novo transcriptome assembly pipeline optimized for gene expression analysis

open access: yesPlant Methods
Background As genomes of many eukaryotic species, especially plants, are large and complex, their de novo sequencing and assembly is still a difficult task despite progress in sequencing technologies.
Aleksandra M. Kasianova   +5 more
doaj   +1 more source

A Study on Using Location-Information-Based Flow Field Reconstruction to Model the Characteristics of a Discharging Valve in a Hydrodynamic Retarder

open access: yesMachines, 2023
In modeling the characteristics of a discharging valve in a hydrodynamic retarder, it is commonly required to determine the value of the flow area to calculate the force on the spool. However, the flow area often relies heavily on empirical or simulation
Wei Wei   +6 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Observation of enhanced transmission for s-polarized light through a subwavelength slit

open access: yes, 2009
Enhanced optical transmission (EOT) through subwavelength apertures is usually obtained for p-polarized light. The present study experimentally investigates EOT for s-polarized light.
A. Yu. Nikitin   +23 more
core   +1 more source

Detection of high levels of congenital transmission of toxoplasma gondii in natural urban populations of mus domesticus [PDF]

open access: yes, 2004
The relative importance of different transmission routes of Toxoplasma gondii has been a matter for debate. This ubiquitous parasite is generally thought to be transmitted by infective oocysts excreted by the definitive host, the cat.
Hide, G   +6 more
core   +1 more source

Lost in transmission…? [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2017
Parasites and pathogens (hereafter referred to collectively as parasites) can have devastating consequences for the individuals they infect, with Ebola and Zika being (at the time of writing) only the most recent examples in a very long list.
Joanne Lello, Andy Fenton
openaire   +5 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

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