Results 71 to 80 of about 1,819,266 (364)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A fast image simulation algorithm for scanning transmission electron microscopy [PDF]
Advanced Structural and Chemical Imaging, 2017 Image simulation for scanning transmission electron microscopy at atomic resolution for samples with realistic dimensions can require very large computation times using existing simulation algorithms.
C. Ophus
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Oriented attachment explains cobalt ferrite nanoparticle growth in bioinspired syntheses
Beilstein Journal of Nanotechnology, 2014 Oriented attachment has created a great debate about the description of crystal growth throughout the last decade. This aggregation-based model has successfully described biomineralization processes as well as forms of inorganic crystal growth, which ...
Annalena Wolff +10 more
doaj +1 more source
, 2018 There is a high demand for fully automated methods for the analysis of primary particle size distributions of agglomerates on transmission electron microscopy images.
Frei, Max, Kruis, Frank Einar
core +1 more source
Electron energy-loss spectrometry on lithiated graphite [PDF]
, 2000 Transmission electron energy-loss spectrometry was used to investigate the electronic states of metallic Li and LiC6, which is the Li-intercalated graphite used in Li-ion batteries.
Ahn, C. C. +3 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Nanoscale diffractive probing of strain dynamics in ultrafast transmission electron microscopy [PDF]
, 2017 The control of optically driven high-frequency strain waves in nanostructured systems is an essential ingredient for the further development of nanophononics. However, broadly applicable experimental means to quantitatively map such structural distortion
da Silva, Nara Rubiano +4 more
core +4 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
CrystalsHigh-energy (710 MeV) Bi ion track morphology in polycrystalline silicon nitride was investigated during post-irradiation annealing. Using both in-situ and ex-situ transmission electron microscopy, we monitored the recovery of crystallinity within ...
Anel Ibrayeva +4 more
doaj +1 more source