Results 71 to 80 of about 1,687,501 (356)

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

In-situ liquid cell transmission electron microscopy investigation on oriented attachment of gold nanoparticles

Nature Communications, 2018
Inside a liquid solution, oriented attachment (OA) is now recognized to be as important a pathway to crystal growth as other, more conventional growth mechanisms.
Chao Zhu, Suxia Liang, E. Song, Yuan Zhou, Wen Wang, Feng Shan, Yantao Shi, C. Hao, K. Yin, Qiu-yi Zhang, J. Liu, Haimei Zheng, Litao Sun   +12 more
semanticscholar   +1 more source

Object Wave Reconstruction by Phase-Plate Transmission Electron Microscopy

, 2010
A method is described for the reconstruction of the amplitude and phase of the object exit wave function by phase-plate transmission electron microscopy.
Blank, H., Dries, M., Gamm, B., Gerthsen, D., Rosenauer, A., Schröder, R. R., Schultheiss, K.   +6 more
core   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

Efficient first principles simulation of electron scattering factors for transmission electron microscopy [PDF]

, 2018
Electron microscopy is a powerful tool for studying the properties of materials down to their atomic structure. In many cases, the quantitative interpretation of images requires simulations based on atomistic structure models. These typically use the independent atom approximation that neglects bonding effects, which may, however, be measurable and of ...
arxiv   +1 more source

Herbal Formula Yi‐Fei‐Jie‐Du‐Tang Regulates Epithelial‐Mesenchymal Transition and Vasculogenic Mimicry in Lung Cancer via HIF1A‐Mediated Ferroptosis

Advanced Biology, Volume 9, Issue 3, March 2025.
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang, Die Yang, Chengjia Yuan, Yang Wu, Qingying Wang, Yongjian Wu, Xiaochun Zhang   +6 more
wiley   +1 more source

Is Small Perfect? Size Limit to Defect Formation in Pyramidal Pt Nanocontacts [PDF]

, 2007
We report high resolution transmission electron microscopy and ab initio calculation results for the defect formation in Pt nanocontacts (NCs). Our results show that there is a size limit to the existence of twins (extended structural defects).
D. S. Galvão, D. Ugarte, F. Sato, N. W. Ashcroft, R. M. Metzger, V. Rodrigues   +5 more
core   +3 more sources

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Metabolic and ultrastructural renal changes in adult Wistar rats fed by a cafeteria diet [PDF]

Acta Cirúrgica Brasileira
Purpose: To evaluate, by quantitative and qualitative methods, the glomerular ultrastructure in Wistar rats fed a cafeteria diet. Methods: Male Wistar rats were divided into two groups at 21 days of age: control (C, n = 10) and cafeteria diet (CAF, n ...
Priscila Fernandes dos Santos, Diogo Benchimol de Souza, Eduardo José Lopes Torres, Waldemar Silva Costa, Francisco José Barcellos Sampaio, Bianca Martins Gregorio   +5 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source