Results 81 to 90 of about 705,883 (316)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

The Experimental And Simulation Analysis Of The Transmission Loss Of The Muffler In The Rotary Compressor

open access: yes, 2012
The discharge muffler of the rotary compressor is used to reduce the discharge noise produced by pressure pulsations. In order to obtain the transmission loss of discharge muffler, four microphone experimental devices used to measure the transmission ...
Xu, Jia, Zhang, Rongting, Gu, Huanhuan
core  

On Machine Learning-Driven Surrogates for Sound Transmission Loss Simulations

open access: yes, 2022
Surrogate models are data-based approximations of computationally expensive simulations that enable efficient exploration of the model's design space and informed decision-making in many physical domains.
Barbara Zaparoli Cunha   +12 more
core   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Exploring acoustic properties of banana fiber composites with elastomeric filler through a computational approach

open access: yesMaterials Research Express
In recent years, there has been a significant increase in the use of natural fibers as reinforcements in composites. This trend is mainly driven by their eco-friendly nature and wide availability.
Prajwal Jayaraman   +5 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Large-scale security constrained optimal reactive power flow for operational loss management on the GB electricity transmission network

open access: yes, 2010
This thesis was submitted for the degree of Engineering Doctorate and awarded by Brunel University, 22/12/2010.The transmission of power across the GB transmission system, as operated by National Grid, results in inevitable loss of electrical power ...
Macfie, Peter
core  

Numerical simulation of transmission loss

open access: yes, 2022
6 S.The transmission loss of thin plates is determined with a coupled FEM-BEM method. Source and receiving room are incorporated explicitly in the numerical model.
Aoki, Yohko   +3 more
core  

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

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