Results 31 to 40 of about 4,945,203 (294)

Should sex-ratio distorting parasites abandon horizontal transmission?

BMC Evolutionary Biology, 2011
Background Sex-ratio distorting parasites are of interest due to their effects upon host population dynamics and their potential to influence the evolution of host sex determination systems.
Ironside Joseph E, Smith Judith E, Hatcher Melanie J, Dunn Alison M   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Investigation of Drive Performance of Motors in Electric Loaders with Unequal Transmission Ratios—A Case Study

World Electric Vehicle Journal
Research on electric wheel loaders (EWLs) has predominantly focused on battery management, hybrid technologies, and energy recovery. However, the influence of motor types and drivetrains on the drive performance of EWLs has received little attention in ...
Xiaotao Fei, Shaw Voon Wong, Muhammad Amin Azman, Peng Liu, Yunwu Han   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Approach for the Calculation of Transmission Ratios and Their Errors in 4-Bar Mechanisms, Considering the Precision Variations by Dimensional Tolerances

AppliedMath
This paper presents research and theoretical development of a mathematical model that, first, allows us to understand how the positional exactitude of the output link of a four-bar mechanism depends on the manufacturing dimensional tolerances.
Javier Flores Méndez, Gustavo M. Minquiz, Alfredo Morales-Sánchez, Mario Moreno, Zaira Jocelyn Hernández Simón, José Alberto Luna López, Francisco Severiano Carrillo, Luis Hernández Martínez, Nancy E. González Sierra, Ana Cecilia Piñón Reyes   +9 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Dual Cone Continuously Variable Transmission Model Controlled by LabVIEW

Machines
This paper outlines the design, development, and practical implementation of a rubber belt-driven dual cone continuously variable transmission (CVT) model. This model enables a demonstration of stepless changes in the transmission ratio between input and
Šimon Berta, Vladimír Goga, Kristián Ondrejička, Erik Kučera, Vladimír Kutiš   +4 more
doaj   +1 more source

Spam1-associated transmission ratio distortion in mice: Elucidating the mechanism

Reproductive Biology and Endocrinology, 2005
Background While transmission ratio distortion, TRD, (a deviation from Mendelian ratio) is extensive in humans and well-documented in mice, the underlying mechanisms are unknown.
Barnoski Barry L, Rulon Michelle, Zhao Yutong, Morales Carlos R, Zhang Hong, Martin-DeLeon Patricia A, Chen Hong, Galileo Deni S   +7 more
doaj   +1 more source