Results 51 to 60 of about 709,315 (265)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Variable Transmission With Actively Controllable Reduction Ratio

IEEE/ASME Transactions on Mechatronics
Actuators that interact with the environment and/or humans require a variable reduction ratio to maintain high motor efficiency over a wide range of output loads. Actively controlled continuous variable transmission (CVT) allows the motor to operate with high efficiency. Most CVT designs have a complex shifting controller design and need high power for
Wonseok Shin, Sungbin Park, Suncheol Kwon, Bummo Ahn, Jung Kim   +4 more
openaire   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Stationary values of the transmission ratio of the planar fourbar

Vietnam Journal of Mechanics, 2008
The transmission ratio of the planar fourbar, i.e. the ratio of the angular velocities of input link and output link, is a function of the input angle. Freudenstein [1] showed how to calculate stationary values of the transmission ratio.
J. Wittenburg
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Transmission ratio distortion results in asymmetric introgression in Louisiana Iris

BMC Plant Biology, 2010
Background Linkage maps are useful tools for examining both the genetic architecture of quantitative traits and the evolution of reproductive incompatibilities.
Knapp Steven J, Okashah Rebecca A, Tang Shunxue, Arnold Michael L, Martin Noland H   +4 more
doaj   +1 more source

Transmission Ratio Distortion in Extended Families

, 2015
A statistical departure from Mendel's law of segregation is known as transmission ratio distortion (TRD). Though well documented in many other organisms, the extent of TRD and its influence in the human genome remains incomplete. Using GAW19 whole genome sequence (WGS) data from 20 large Mexican American pedigrees, our goal was to identify potentially ...
Bhatnagar, Sahir, Celia Greenwood, Labbe, Aurélie   +2 more
openaire   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Analisis Kinerja MIMO Masif dengan Teknik Precoding Maximum Ratio Transmission

Jurnal Nasional Teknik Elektro dan Teknologi Informasi, 2019
Channel State Information (CSI) at the base stations obtained via the uplink training is an important factor in cellular and multiuser Multi-Input Multi-Output (MIMO) communication networks. In massive MIMO cellular networks with pilotbased training, the
Rusdha Muharar
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source