Results 41 to 50 of about 4,945,203 (294)

Ratio Shared Task 2019

open access: yes, 2019
<p>Ratio Shared Task 2019:</p> <p>Task 1 (same side classification)</p> <p> </p> <p>Task 2 (stance classification)</p ...
RATIO
core   +1 more source

The impact of realistic age structure in simple models of tuberculosis transmission [PDF]

open access: yes, 2010
Background : Mathematical models of tuberculosis (TB) transmission have been used to characterize disease dynamics, investigate the potential effects of public health interventions, and prioritize control measures.
Ted Cohen   +9 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Research on Meshing Efficiency of Gear Pairs Based on Dynamic Sliding Friction Factors

open access: yesJixie chuandong, 2023
In order to study the meshing efficiency of the gear pair under the actual working conditions, the force and kinematics of the contact surface of the gear pair are analyzed, the lubrication state of the gear pair is judged by combining the theory of ...
Fu Jingbo   +3 more
doaj  

Effect of strain and inoculation dose of classical swine fever virus on within-pen transmission. [PDF]

open access: yes, 2009
To improve the understanding of the dynamics and options for control of classical swine fever (CSF), more quantitative knowledge is needed on virus transmission.
Loeffen, W.L.A.   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Two-Speed Transmission Structure and Optimization Design for Electric Vehicles

open access: yesMachines, 2023
The trend in the global automotive industry is moving towards electric vehicles that do not emit exhaust gases and use eco-friendly fuel. Electric vehicles are more eco-friendly compared to internal combustion engine vehicles, as they emit less carbon ...
Wonhyeong Jeong   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

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