Results 51 to 60 of about 1,647,817 (351)

Rethinking Transparency and Rigor from a Qualitative Open Science Perspective

open access: yesJournal of Trial and Error, 2023
Discussions around transparency in open science focus primarily on sharing data, materials, and coding schemes, especially as these practices relate to reproducibility.
Crystal Steltenpohl   +6 more
doaj   +1 more source

Decisive test of color transparency in exclusive electroproduction of vector mesons

open access: yes, 1993
The exclusive production of vector mesons in deep inelastic scattering is a hard scattering process with the well controlled size of quark configurations which dominate the production amplitude. This allows an unambiguous prediction of color transparency
Amaudruz   +30 more
core   +1 more source

Seeking transparency [PDF]

open access: yesNature Medicine, 2010
A more transparent drug approval process has the potential to reduce cost and duplicated effort, as well as ultimately improve access to effective treatments for patients.
openaire   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

State capture through indemnification demands? Effects on equity in the global distribution of COVID-19 vaccines

open access: yesJournal of Pharmaceutical Policy and Practice, 2022
Background State capture by the pharmaceutical industry is a form of corruption whereby pharmaceutical companies shift laws or policies about their products away from the best interest of the public and toward their private benefit.
Ariel Gorodensky, Jillian C. Kohler
doaj   +1 more source

Privacy, Visibility, Transparency, and Exposure [PDF]

open access: yes, 2008
This essay considers the relationship between privacy and visibility in the networked information age. Visibility is an important determinant of harm to privacy, but a persistent tendency to conceptualize privacy harms and expectations in terms of ...
Cohen, Julie E.
core   +2 more sources

Transparent and non-transparent languages [PDF]

open access: yesFolia Linguistica, 2018
Abstract Languages differ widely from one another in the extent to which they are transparent, i.e. obey one-to-one relationships between meaning and form. Transparency, in turn, is an important factor in the learnability of languages. This paper first sets out a framework for the study of transparency and subsequently studies cross-linguistic ...
Hengeveld, K., Leufkens, S.
openaire   +5 more sources

Patatin‐domain‐containing (phospho)lipases under control: Mammalian co‐regulators and pathogenic activation mechanisms

open access: yesFEBS Open Bio, EarlyView.
Patatin domain‐containing (phospho)lipases are lipid‐hydrolyzing enzymes central to metabolism, membrane remodeling, and signaling. Their activity relies on precise co‐activation mechanisms involving protein–protein interactions and conformational rearrangements.
Noopur Dubey   +2 more
wiley   +1 more source

Comparison of treatment effect sizes from pivotal and postapproval trials of novel therapeutics approved by the FDA based on surrogate markers of disease: a meta-epidemiological study

open access: yesBMC Medicine, 2018
Background The U.S. Food and Drug Administration (FDA) often approves new drugs based on trials that use surrogate markers for endpoints, which involve certain trade-offs and may risk making erroneous inferences about the medical product’s actual ...
Joshua D. Wallach   +6 more
doaj   +1 more source

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