Results 81 to 90 of about 1,738,280 (381)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Comparison of treatment effect sizes from pivotal and postapproval trials of novel therapeutics approved by the FDA based on surrogate markers of disease: a meta-epidemiological study

BMC Medicine, 2018
Background The U.S. Food and Drug Administration (FDA) often approves new drugs based on trials that use surrogate markers for endpoints, which involve certain trade-offs and may risk making erroneous inferences about the medical product’s actual ...
Joshua D. Wallach, Oriana Ciani, Alison M. Pease, Gregg S. Gonsalves, Harlan M. Krumholz, Rod S. Taylor, Joseph S. Ross   +6 more
doaj   +1 more source

EURAD EC project – overview of the routes work package: identified key issues and open questions about waste management routes in Europe, from cradle to grave

EPJ Nuclear Sciences & Technologies, 2023
The ROUTES Work Package (WP) is one of the two strategic studies being conducted as part of the European Joint Programme on Radioactive Waste Management (EURAD). ROUTES’ objectives are (i) to provide a framework for European Union’s member states (MS) to
Marsal François, Leoni Elisa, Bornhoeft Marie-Charlotte, Coninx Stefan, De Bock Chris, Feinhals Joerg, Harvey Elizabeth, Kastbjerg Nielsen Ole, Kutina Iryna, Maitre Mélanie, Mikšová Jitka, Rooses Adrien, Savidou Anastasia, Swahn Johan, Vuorio Marja, Wasselin Virginie, Železnik Nadja   +16 more
doaj   +1 more source

LANTERN TRANSPARENCIES [PDF]

Science, 1897
n ...
openaire   +3 more sources

Evaluating feature extraction reproducibility across image biomarker standardization initiative‐compliant radiomics platforms using a digital phantom

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The aim of this study was to thoroughly analyze the reproducibility of radiomics feature extraction across three Image Biomarker Standardization Initiative (IBSI)‐compliant platforms using a digital phantom for benchmarking. It uncovers high consistency among common features while also pointing out the necessity for standardization ...
Han‐Back Shin, Heesoon Sheen, Jang‐Hoon Oh, Young Eun Choi, Kihoon Sung, Hyun Ju Kim   +5 more
wiley   +1 more source

The transparency of creoles [PDF]

Journal of Pidgin and Creole Languages, 2013
In this article I propose that creoles are relatively transparent compared to their source languages. This means that they display more one-to-one relations between meaning and form. Transparency should be distinguished from the concepts of simplicity, ease of acquisition, and regularity.
openaire   +6 more sources

AAPM medical physics practice guideline 13.a: HDR brachytherapy, part B

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract The goal of this report is to assist the clinical medical physicist in assuring that key quality standards and practice considerations are met to ensure safe, reliable, and reproducible high dose rate (HDR) brachytherapy (BT) treatment. This guideline has been developed to provide appropriate minimum standards for such services.
Susan L. Richardson, Arjit K. Baghwala, Gil'ad N. Cohen, Claire Dempsey, Bruce Libby, Christopher S. Melhus, Robin A. Miller, Daniel J. Scanderbeg, Samantha J. Simiele   +8 more
wiley   +1 more source

Application of machine learning methods for predicting infant mortality in Rwanda: analysis of Rwanda demographic health survey 2014–15 dataset

BMC Pregnancy and Childbirth, 2022
Background Extensive research on infant mortality (IM) exists in developing countries; however, most of the methods applied thus far relied on conventional regression analyses with limited prediction capability. Advanced of Machine Learning (AML) methods
Emmanuel Mfateneza, Pierre Claver Rutayisire, Emmanuel Biracyaza, Sanctus Musafiri, Willy Gasafari Mpabuka   +4 more
doaj   +1 more source

Transparency in the transparency reports: Empirical evidence from Portugal

Intangible Capital, 2022
Purpose: The purpose of this research is to analyze the degree of TR transparency and its relation with the audit firm size, fees, either from audit services, or from other services, and with the human capital. Design/methodology/approach: In this study
Bruno Almeida, Ana Filipa Silva, Clara Margarida Viseu   +2 more
doaj   +1 more source

Transparency in artificial intelligence

Internet Policy Review, 2020
This conceptual paper addresses the issues of transparency as linked to artificial intelligence (AI) from socio-legal and computer scientific perspectives.
S. Larsson, F. Heintz
semanticscholar   +1 more source