Results 21 to 30 of about 503 (69)
MedComm – Biomaterials and Applications, Volume 4, Issue 4, December 2025.Vitamin‐derived nanoplatforms advance precision oncology by augmenting immunotherapy through dendritic cell activation, T‐cell reprogramming, and TME remodeling to enhance antitumor immunity, while enabling targeted therapeutic delivery. These systems integrate theranostic capabilities using vitamin‐conjugated imaging probes for concurrent tumor ...
Ruowa Xu +3 more
wiley +1 more source
Immune Surveillance and Immune Escape in Cancer: Mechanisms and Immunotherapy
MedComm, Volume 6, Issue 10, October 2025.Our review focused on how specific cellular subsets crucial for igniting tumor immunity cycle, notably effector and helper T cells alongside antigen presentation cells, interact closely in both antigen‐dependent and ‐independent manners (within centered ring) adjacent to cancer cells.
Ying Peng +21 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 8, Page 925-930, August 2025.Summary The immunosuppressive and immunomodulatory treatment of dermatological patients necessitates the regular review and updating of standard vaccinations and vaccines indicated for specific conditions. The German Standing Committee on Vaccination (STIKO) at the Robert Koch Institute regularly publishes evidence‐based vaccination recommendations ...
Johanna Stoevesandt +3 more
wiley +1 more source
Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets
MedComm, Volume 6, Issue 7, July 2025.Natural compounds modulate the TGF‐β pathway, which acts as both a tumor suppressor and promoter during cancer progression. Agents such as ginsenosides, halofuginone, and EGCG influence cell proliferation, apoptosis, and angiogenesis. These bioactive molecules may complement standard therapies, highlighting the need for advanced formulations ...
Reham Hassan Mekky +9 more
wiley +1 more source
Cell Biology of Human Cytomegalovirus Latency: Implications for Pathogenesis and Treatment
Reviews in Medical Virology, Volume 35, Issue 4, July 2025.ABSTRACT Human cytomegalovirus (HCMV), like all herpes viruses, can establish lifelong infections of the host. This is due to the capacity to establish latency—a defining characteristic of herpes virus infection. In healthy individuals, pathology associated with HCMV infection is rare due, in part, to a robust immune response that controls replication.
Matthew B. Reeves
wiley +1 more source
Intrathymic Regulation of Dendritic Cell Subsets and Their Contributions to Central Tolerance
Immunological Reviews, Volume 332, Issue 1, July 2025.ABSTRACT Thymic dendritic cells (DCs) are critical mediators of central tolerance, cooperating with medullary thymic epithelial cells (mTECs) and B cells to establish T‐cell self‐tolerance to the proteome. The DC compartment is highly heterogeneous and is comprised of three major subsets, plasmacytoid dendritic cells (pDCs) and two conventional ...
Aparna Calindi, Lauren I. R. Ehrlich
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.ABSTRACT Advances in biotechnology are set to revolutionise the treatment of haematological malignancies. Current treatments have limited efficacy due to their high toxicity and poor long‐term outcomes, particularly in acute myeloid leukaemia (AML). In 2024–2025, emerging targeted therapies promise improved results with reduced adverse effects.
Akbar M. Shahid +2 more
wiley +1 more source
Dissection of Neurochemical Pathways Across Complexity and Scale
Journal of Neurochemistry, Volume 169, Issue 7, July 2025.The field of Neurochemistry spent decades trying to understand how the brain works, and many recent technological advancements have allowed researchers to unlock some mysteries of the brain. This review, which was written by attendees of the Advanced School hosted by the International Society of Neurochemistry in 2023, summarizes these technological ...
Alice Abbondanza +30 more
wiley +1 more source
Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Predictive markers for efficiency of the amino-acid deprivation therapies in cancer. [PDF]
Front Med (Lausanne), 2022 Pokrovsky VS +3 more
europepmc +1 more source