Results 101 to 110 of about 29,448 (249)

Aryl Hydrocarbon Receptor in Health and Disease

MedComm, Volume 6, Issue 11, November 2025.
Based on the structure and ligands of AhR, this review introduces the AhR‐related signaling pathways and their roles in health and diseases. Agonists and antagonists of AhR as well as new strategies for treatment using the microbial–AhR axis are summarized. A prospect was made for the future use of AhR as a therapeutic target.
Haonan Li, Yufeng Fan, Jizheng Liu, Shumin Dong, Bin Wen, Yunfei Zhang, Xiaocui Wang, Xuemei Duan, Ying Hu, Ze Yan, Huifeng Shang, Yukai Jing   +11 more
wiley   +1 more source

Análise do comportamento biológico de heteroenxertos descelularizados e homoenxertos criopreservados: estudo em ovinos Decellularized heterografts versus cryopreserved homografts: experimental study in sheep model

Brazilian Journal of Cardiovascular Surgery, 2009
OBJETIVO: Este estudo avalia o comportamento biológico dos heteroenxertos porcinos descelularizados (Grupo Desc) comparados com os homoenxertos criopreservados (Grupo Crio) implantados em carneiros jovens.
Sergio Augusto Veiga Lopes, Francisco Diniz Affonso da Costa, Josué Brudginski de Paula, Pascal Dhomen, Felipe Phol, Ricardo Vilani, João Gabriel Roderjan, Eduardo Discher Vieira   +7 more
doaj   +1 more source

Studies on leukemia in the C3Hf strain of mice,2. [PDF]

, 1963
Spontaneous C3Hf lymphatic leukemia maintained in an ascites form was transplanted into newborn Wistar rats less than 24 hours old. Single subcutaneous or intraperitoneal inoculation of the neoplastic cells resulted in progressive tumor growth fatal to ...
Miyoshi, Isao
core   +1 more source

Confirmation of the Enhancement Effect of ANCE Treatment on Functional Recovery of Manual Dexterity From Primary Motor Cortex (M1) Lesion in Adult Macaque Monkeys

Brain and Behavior, Volume 15, Issue 10, October 2025.
Together, an earlier pilot study and the current confirmatory study show that an autologous cellular therapy promotes beneficial, significant enhancement of manual dexterity recovery after lesion of the primary motor cortex. ABSTRACT Introduction A pilot study provided preliminary evidence indicating that peri‐lesional adult autologous neural cell ...
Camille Roux, Julie Savidan, Jean‐François Brunet, Jocelyne Bloch, Eric M. Rouiller, Eric Schmidlin, Mélanie Kaeser   +6 more
wiley   +1 more source

Current status and future perspectives of multi‐modal bacteria‐based cancer therapies

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Bacteria exhibit inherent tumour‐targeting capabilities, particularly thriving in hypoxic tumour microenvironments (TMEs) and activating potent anti‐tumour immune responses through pathogen‐associated molecular patterns (PAMPs) and immunomodulation.
Shuai Fan, Siyu Zhu, Wenyu Wang, Yuetong Liu, Yutong Zhou, Hao Li, Bofeng Liu, Qin Xia, Lili Huang, Lei Dong   +9 more
wiley   +1 more source

Targeting the Ubiquitin–Proteasome System for Cancer

MedComm, Volume 6, Issue 10, October 2025.
This figure shows the mechanism of protein degradation by ubiquitin–proteasome system. The process begins with ubiquitin activation by the E1 enzyme, forming a thioester bond between E1's cysteine residue and ubiquitin's glycine carboxyl group, powered by ATP hydrolysis.
Zhaoyun Liu, Jiao Lai, Ziyu Ma, Jianhua Pan, Chun Yang, Rong Fu   +5 more
wiley   +1 more source

Teratoid Hepatoblastoma: Clinicopathologic Features and Outcomes

Pediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Background Teratoid hepatoblastoma (HB) is a rare histologic subtype of the most common pediatric liver cancer. Understanding of the clinicopathologic features and outcomes of patients with this disease is currently limited. Methods Multi‐institution, retrospective chart review was conducted to compare 20 children with teratoid HB to 129 ...
Brian T. Hickner, Andres F. Espinoza, Soo Jin Cho, Stephen Sarabia, Martin Urbicain, Ann Wang, Sanjeev A. Vasudevan, Dolores H. López‐Terrada, Kalyani R. Patel   +8 more
wiley   +1 more source

Ctrl-X, Ctrl-C and Ctrl-V in Veterinary Dermatology: Skin microbiota transplantation as a promising approach for dogs with cutaneous adverse food reactions

Analecta Veterinaria
The probability of influencing the skin microbiome for addressing skin disorders opens a novel aisle of therapy. This study aimed to evaluate the efficacy of skin microbiota transplantation (sMt) for cutaneous adverse food reactions (caFr) in dogs.
Kerem Ural, Hasan Erdoğan, Songül Erdoğan   +2 more
doaj   +1 more source

A Scoping Review of Pathogenesis, Current Treatments, and Novel Approaches for Vitiligo

Journal of Cosmetic Dermatology, Volume 24, Issue 10, October 2025.
ABSTRACT Background Vitiligo is a chronic skin disorder characterized by loss of melanocytes, causing depigmentation and psychological distress. Its pathogenesis is complex and multifactorial, involving genetic predisposition, autoimmune, oxidative stress, and neurogenic mechanisms.
Nusaibah Sallehuddin, Nur Izzah Md Fadilah, Mh Busra Fauzi, Manira Maarof   +3 more
wiley   +1 more source

Rootstock of distant hybrid activates transcription factors of scion cultivar to promote growth and yield in walnut

Plant Biotechnology Journal, Volume 23, Issue 10, Page 4302-4317, October 2025.
Summary Walnut (Juglans regia L.) is a significant commercial tree, valued both for its timber and nut production and it is extensively cultivated across the globe. We exploit heterografting by using cultivar‐‘Shangsong14’ (Juglans regia; ‘S14’) as scion and hybrid elite‐‘Zhongningqi’ (Juglans hindsii × Juglans regia; ‘Q’) as rootstock and self ...
Baoxin Li, Yueying Liu, Pu Zhang, Xiaobo Song, Xinyu Wang, Zhimin Zheng, Dong Pei   +6 more
wiley   +1 more source