Results 71 to 80 of about 464,363 (247)

Chicken Testicular Stem Cells

The Journal of Poultry Science, 2012
Transplantation of male germ cells into sterilized recipients in chicken opened a new approach for chicken transgenesis as well as for preservation of endangered bird species.
Pavel Trefil, Jitka Mucksová, Jiri Kalina   +2 more
doaj   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Tacrolimus and cyclosporine have differential effects on the risk of development of bronchiolitis obliterans syndrome: results of a prospective, randomized international trial in lung transplantation.

, 2012
Chronic lung allograft dysfunction, which manifests as bronchiolitis obliterans syndrome (BOS), is recognized as the primary cause of morbidity and mortality after lung transplantation.
Klepetko, Walter, European and Australian Investigators in Lung Transplantation, Glanville, A.R., Aubert, John-David, Knoop, C., Vettorazzi, Eik, Aubert, J.D., Aboyoun, Christina, Klepetko, W., Vettorazzi, E., Reichenspurner, H., Reichenspurner, Hermann, Treede, Hendrik, Glanville, Allan R., Knoop, Christiane, Bravo, Carlos, Lama, Raffael, Lama, R., European,, Aboyoun, C., Bravo, C., Treede, H.   +21 more
core   +1 more source

Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse [PDF]

, 2012
This report describes the clinical courses of two acute myeloid leukemia patients. Both had MLL translocations, the first a t(10;11)(p11.2;q23) with MLL-AF10 and the second a t(11;19)(q23;p13.1) with MLL-ELL fusion.
Meyer, Claus, Carola Tietze-Bürger, Claus Meyer, Igor Blau, Burmeister, Thomas, Molkentin, Mara, Thomas Burmeister, Mara Molkentin, Nils Lachmann, Uharek, Lutz, Rolf Marschalek, Tietze-Bürger, Carola, Friedrichs, Birte, Blau, Igor Wolfgang, Jörg Beyer, Marschalek, Rolf, Schwartz, Stefan, Lutz Uharek, Beyer, Jörg, Stefan Schwartz, Gunnar Lohm, Birte Friedrichs, Lachmann, Nils, Lohm, Gunnar   +23 more
core   +1 more source

Generation of Transplantable Beta Cells for Patient-Specific Cell Therapy

International Journal of Endocrinology, 2012
Islet cell transplantation offers a potential cure for type 1 diabetes, but it is challenged by insufficient donor tissue and side effects of current immunosuppressive drugs.
Xiaojie Wang, Daniel L. Metzger, Mark Meloche, Jianqiang Hao, Ziliang Ao, Garth L. Warnock   +5 more
doaj   +1 more source

Activation of immune signals during organ transplantation

Signal Transduction and Targeted Therapy, 2023
The activation of host’s innate and adaptive immune systems can lead to acute and chronic graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to clarify the immune signals, which are critical to the initiation ...
Qingwen Li, Peixiang Lan
doaj   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Liver transplantation in primary biliary cirrhosis: Risk assessment and 11-year follow-up [PDF]

, 2000
Background/Aims: Liver transplantation (LTx) is the only established treatment in patients with end-stage primary biliary cirrhosis (PBC). Although short-term survival after LTx in this group of patients is usually good, few data exist on the long-term ...
Paumgartner, Gustav, Pape, G. R., Rau, Horst, Pape, Gerd R., Rau, H., Paumgartner, G., Gerbes, Alexander L., Schildberg, F. W., Rust, C., Beuers, Ulrich, Haller, M., Krämling, H., Schildberg, Friedrich Wilhelm, Haller, Matthias, Gerbes, A. L., Krämling, Hans-Jörg, Beuers, U., Rust, Christian   +17 more
core   +1 more source

Heterologous Cytomegalovirus and Allo-Reactivity by Shared T Cell Receptor Repertoire in Kidney Transplantation

Frontiers in Immunology, 2019
Cytomegalovirus (CMV) infection is associated with allograft rejection but the mechanisms behind are poorly defined yet. Although cross-reactivity of T cells to alloantigen and CMV has been hypothesized, direct evidence in patients is lacking.
Lucia Stranavova, Ondrej Pelak, Michael Svaton, Petra Hruba, Eva Fronkova, Antonij Slavcev, Klara Osickova, Jana Maluskova, Petr Hubacek, Jiri Fronek, Petra Reinke, Hans-Dieter Volk, Tomas Kalina, Ondrej Viklicky, Ondrej Viklicky   +14 more
doaj   +1 more source

Characterization of a novel R98Q mutation that confers resistance to sulfentrazone in common ragweed (Ambrosia artemisiifolia) populations from Michigan

Pest Management Science, EarlyView.
Field‐collected Ambrosia artemisiifolia populations from Michigan, USA, soybean fields exhibited strong resistance to the protoporphyrinogen IX oxidase (PPO)‐inhibiting herbicide sulfentrazone and reduced sensitivity to fomesafen. Target‐site analysis identified a novel Arg‐98‐Gln (R98Q) substitution in PPO2, co‐occurring with the previously reported ...
Sara Álvarez‐Rodríguez, Michael Ozolins, Aimone Porri, Jens Lerchl, Eric Patterson   +4 more
wiley   +1 more source