Results 51 to 60 of about 17,369 (237)

Embryonic Cell Grafts in a Culture Model of Spinal Cord Lesion: Neuronal Relay Formation is Essential for Functional Regeneration

Frontiers in Cellular Neuroscience, 2016
Presently there exists no cure for spinal cord injury. However, transplantation of embryonic tissue into spinal cord lesions resulted in axon outgrowth across the lesion site and some functional recovery, fostering hope for future stem cell therapies ...
Anne Tscherter, Martina Heidemann, Sonja Kleinlogel, Jürg Streit   +3 more
doaj   +1 more source

Engraftment of sheep splenic lymphocytes into NBSGW mice and application in Brucella infection

Animal Models and Experimental Medicine, EarlyView.
A sheep splenocyte‐reconstituted mouse model (Sh‐Spl mice) was established via intravenous injection of sheep splenic lymphocytes into immunodeficient mice to evaluate Brucella infection. Abstract Background The development of immune reconstituted xenograft mouse models has addressed the limitations imposed by interspecies immunological differences in ...
Xiaowei Wang, Shicheng Wan, Yanmin Guo, Hongyu Han, Fei Luo, Dongmei Jiang, Xiaorong Yang, Quanhai Pang, Haisheng Yu, Jinlian Hua   +9 more
wiley   +1 more source

Lung Transplant Recipients Immunogenicity after Heterologous ChAdOx1 nCoV-19—BNT162b2 mRNA Vaccination [PDF]

, 2022
(1) Background: High immunosuppressive regimen in lung transplant recipients (LTRs) hampers the immune response to vaccination. We prospectively investigated the immunogenicity of heterologous ChAdOx1 nCoV-19-BNT162b2 mRNA vaccination in an LTR cohort ...
Bayart, Jean-Louis, Constant Gillot, Patrick Evrard, Douxfils, Jonathan, Catry, Emilie, Frérotte, Damien, Carlier, François, Emilie Catry, Gillot, Constant; id_orcid, Dumonceaux, Michel, Jonathan Douxfils, Damien Frérotte, Favresse, Julien, Jean-Louis Bayart, Douxfils, Jonathan; id_orcid, Julien Favresse, Closset, Mélanie, Carlier, François M, François Mullier, Michel Dumonceaux, Evrard, Patrick, Mélanie Closset, Mullier, François, Carlier, François M., Gillot, Constant, François M. Carlier   +25 more
core   +1 more source

Living Microbial Drugs

Chemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik, Nazlıcan Tunç, Senem Şen, Urartu Özgür Şafak Şeker   +3 more
wiley   +1 more source

Development of α 1,3-galactosyltransferase Inactivated and Human Membrane Cofactor Protein Expressing Homozygous Transgenic Pigs for Xenotransplantation

Journal of Animal Reproduction and Biotechnology, 2017
Transplantation is considered to be a very useful approach to improve human welfare and to prolong life-span. Heterologous organ transplantation using pig organs which are similar to human beings and easy to make mass-production has known as one of the ...
Gunsup Lee, Sang Hyoun Park, Haesun Lee, Soo-Jeong Ji, Joo Yung Lee, Sung-June Byun, Seongsoo Hwang, Kyung Woon Kim, Sun A Ock, Keon Bong Oh   +9 more
doaj   +1 more source

In vivo behaviour of human precursors into a dystrophic context [PDF]

, 2013
The Duchenne Muscular Dystrophy (DMD) is a lethal recessive X-linked disease caused by mutations in the dystrophin gene, no effective treatment is available up to date.
Vallese, Denis
core  

Mass culture of equine synovial fluid‐derived mesenchymal stromal cells using nonwoven polyethylene terephthalate fabrics

Equine Veterinary Journal, EarlyView.
Abstract Background Culture protocols need to yield 100 million equine synovial fluid (SF)‐derived mesenchymal stromal cells (SF‐MSCs) in around 3 weeks are needed, before these cells can be evaluated as agents of articular repair in clinical trials. Objectives To investigate mass culture of equine SF‐MSC culture protocols using nonwoven polyethylene ...
Miho Daniel Yoshitomi, Tomohide Kuramoto, Takashi Hatazoe, Kenta Mitsuda, Henry Smith, Kazuhiro Misumi   +5 more
wiley   +1 more source

Influence of Clinical and Psychosocial Factors on the Acceptance of no Human Organs in Transplants: Xenotransplants

Brazilian Journal of Transplantation, 2022
Introduction: Xenotransplantation is defined as the transplantation of cells, organs and tissues between different species. It is studied as an alternative method to acquire an adequate supply of human organs, which imbalance in demand results in ...
Cinthia Laureano Pavan, Moacir Fernandes de Godoy, Eliane Tiemi Miyazaki, Rita de Cassia Martins Alves da Silva, Caio Hussid de Goes, Lilian Castiglioni, Renato Ferreira da Silva   +6 more
doaj  

Chicken Testicular Stem Cells

The Journal of Poultry Science, 2012
Transplantation of male germ cells into sterilized recipients in chicken opened a new approach for chicken transgenesis as well as for preservation of endangered bird species.
Pavel Trefil, Jitka Mucksová, Jiri Kalina   +2 more
doaj   +1 more source

Activation of immune signals during organ transplantation

Signal Transduction and Targeted Therapy, 2023
The activation of host’s innate and adaptive immune systems can lead to acute and chronic graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to clarify the immune signals, which are critical to the initiation ...
Qingwen Li, Peixiang Lan
doaj   +1 more source