Results 41 to 50 of about 464,363 (247)

Regulatory immune cells in transplantation. [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew, Wood, Kathryn, Bushell, A, Hester, J, Wood, Kathryn J, Andrew Bushell, Joanna Hester, Kathryn J. Wood, Wood, KJ, Hester, Joanna   +9 more
core   +1 more source

T Cell Repertoire Maturation Induced by Persistent and Latent Viral Infection Is Insufficient to Induce Costimulation Blockade Resistant Organ Allograft Rejection in Mice

Frontiers in Immunology, 2018
CD28:CD80/86 pathway costimulation blockade (CoB) with the CD80/86-specific fusion protein CTLA4-Ig prevents T cell-mediated allograft rejection in mice.
Jaclyn R. Espinosa, Jaclyn R. Espinosa, Danny Mou, Bartley W. Adams, Louis R. DiBernardo, Andrea L. MacDonald, MacKenzie McRae, Allison N. Miller, Mingqing Song, Linda L. Stempora, Jun Wang, Neal N. Iwakoshi, Allan D. Kirk   +12 more
doaj   +1 more source

Liver Transplantation With Livers From Octogenarians and a Nonagenarian

, 2015
Introduction. A shortage of deceased donors has compelled the use of extended-criteria donor organs in liver transplantation.
ÜNAL, BÜLENT, YILMAZ, SEZAİ, Onur, Asım, Soyer, V., Sarıcı, Kemal Barış, Onur, A., Yağcı, Mehmet Ali, DİRİCAN, ABUZER, Yılmaz, Sezai, SARICI, KEMAL BARIŞ, Yagci, M. A., Koc, SÜLEYMAN, Soyer, Vural   +12 more
core   +1 more source

Combination of heterologous fibrin sealant and bioengineered human embryonic stem cells to improve regeneration following autogenous sciatic nerve grafting repair

Journal of Venomous Animals and Toxins including Tropical Diseases, 2018
Background Peripheral nerve injury is a worldwide clinical problem, and the preferred surgical method for treating it is the end-to-end neurorrhaphy. When it is not possible due to a large nerve gap, autologous nerve grafting is used.
Roghayeh Mozafari, Sergiy Kyrylenko, Mateus Vidigal Castro, Rui Seabra Ferreira, Benedito Barraviera, Alexandre Leite Rodrigues Oliveira   +5 more
doaj   +1 more source

Induced Foxp3+ T cells colonising tolerated allografts exhibit the hypomethylation pattern typical of mature regulatory T cells.

Frontiers in Immunology, 2016
Regulatory T cells expressing the transcription factor Foxp3 require acquisition of a specific hypomethylation pattern to ensure optimal functional commitment, limited lineage plasticity and long-term maintenance of tolerance.
Robert eHilbrands, Ye eChen, Adrian eKendal, Elizabeth eAdams, Stephen Paul Cobbold, Herman eWaldmann, Duncan eHowie   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cellular and Humoral SARS-CoV-2 Vaccination Responses in 192 Adult Recipients of Allogeneic Hematopoietic Cell Transplantation

Vaccines, 2022
To determine factors influencing the vaccination response against SARS-CoV-2 is of importance in recipients of allogeneic hematopoietic cell transplantation (allo-HCT) as they display an increased mortality after SARS-CoV-2 infection, an increased risk ...
Thomas Meyer, Gabriele Ihorst, Ingrid Bartsch, Robert Zeiser, Ralph Wäsch, Hartmut Bertz, Jürgen Finke, Daniela Huzly, Claudia Wehr   +8 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The International Liver Transplantation Society living donor liver transplant recipient guideline

, 2017
Living donor liver transplantation (LDLT) has been increasingly embraced around the world as an important strategy to address the shortage of deceased donor livers.
Lo, CM, Quintini, Cristiano, Lee, SG, Durand, F, Kyrana, E, Lerut, J, Kyrana, Eirini, Lee, Sung-Gyu, Kim-Schluger, HL, Quintini, C, Kim-Schluger, Hyung Leona, Pomfret, Elizabeth Anne, Heimbach, Julie K, Lerut, Jan, Miller, Charles M, Dhawan, A, Dhawan, Anil, Durand, Francois, Lo, Chung-Mau, Miller, CM, Heimbach, JK, Pomfret, EA   +21 more
core   +1 more source

Complete Microbiota Engraftment Is Not Essential for Recovery from Recurrent Clostridium difficile Infection following Fecal Microbiota Transplantation

mBio, 2016
Bacterial communities from subjects treated for recurrent Clostridium difficile infection (rCDI) by fecal microbiota transplantation (FMT), using either heterologous donor stool samples or autologous stool samples, were characterized by Illumina next ...
Christopher Staley, Colleen R. Kelly, Lawrence J. Brandt, Alexander Khoruts, Michael J. Sadowsky   +4 more
doaj   +1 more source