Results 41 to 50 of about 29,252 (243)
Animal Models and Experimental Medicine, EarlyView.To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang +7 more
wiley +1 more source
The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts
Frontiers in Immunology, 2018 The immune suppressants cyclosporin A (CsA) and tacrolimus (FK506) are used worldwide in transplantation medicine to suppress graft rejection. Both CsA and FK506 inhibit the phosphatase calcineurin (CN) whose activity controls the immune receptor ...
Johannes Baur +12 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Cell Transplantation, 1994 The distribution of acetylcholinesterase (AChE) at the ultrastructural level was investigated in normal and in pancreatic fragments transplanted for 56 days into the anterior eye chamber of heterologous rats using enzyme cytochemical methods ...
Ernest Adeghate, Tibor Donáth
doaj +1 more source
Developmental Dynamics, EarlyView.Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore +7 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Culture protocols need to yield 100 million equine synovial fluid (SF)‐derived mesenchymal stromal cells (SF‐MSCs) in around 3 weeks are needed, before these cells can be evaluated as agents of articular repair in clinical trials. Objectives To investigate mass culture of equine SF‐MSC culture protocols using nonwoven polyethylene ...
Miho Daniel Yoshitomi +5 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2016 Presently there exists no cure for spinal cord injury. However, transplantation of embryonic tissue into spinal cord lesions resulted in axon outgrowth across the lesion site and some functional recovery, fostering hope for future stem cell therapies ...
Anne Tscherter +3 more
doaj +1 more source
Liver Transplantation for Budd-Chiari Syndrome [PDF]
, 1976 Orthotopic liver transplantation was accomplished in a 22-year-old woman dying of the Budd-Chiari syndrome. She is well and has normal liver function 16 months postoperatively.
Porter, KA +4 more
core +1 more source
Interdisciplinary Medicine, EarlyView.Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi +6 more
wiley +1 more source
Skin Transplantation and Lymphoid Organ Analysis in Mice
Bio-Protocol, 2020 Skin transplantation in mice is an important procedure to evaluate immune responses generated against heterologous grafts, especially given its highly immunogenic nature. In fact, skin is one of the most challenging organs in terms of allograft retention.
Julie Ruer-Laventie +4 more
doaj +1 more source