Results 21 to 30 of about 17,369 (237)

Organs from animals for man [PDF]

open access: yes, 1998
In the following review some of the problems of xenotransplantation shall be discussed, based on the few experimental data available so far and on reports in the literature describing investigations which may be of importance for xenotransplantation. The
Diefenbeck, M.   +3 more
core   +1 more source

Establishment of Etv5 gene knockout mice as a recipient model for spermatogonial stem cell transplantation

open access: yesBiology Open, 2021
Spermatogonial stem cell (SSC) transplantation is an alternative reproductive method to achieve conservation and production of elite animals in livestock production. Creating a recipient animal without endogenous germ cells is important for effective SSC
Xianyu Zhang   +8 more
doaj   +1 more source

Potential of Adipose-derived stem cells in muscular regenerative therapies

open access: yesFrontiers in Aging Neuroscience, 2015
Regenerative capacity of skeletal muscles resides in satellite cells, a self-renewing population of muscle cells. Several studies are investigating epigenetic mechanisms that control myogenic proliferation and differentiation to find new approaches that ...
Sonia eForcales
doaj   +1 more source

Intracranial transplantation of the tumor induced by adenovirus type 12 in Syrian hamster--an experimental brain tumor model

open access: yes, 1971
A method of intracranial transplantation of the tumor induced by adenovirus type 12 in syrian hamster has been described. The incidence of intracranial tumor development was 86 (90.5 %) out of 95 animals and the average survival time and tumor size at ...
Tabuchi, Kazuo
core   +1 more source

Surgical Options for Aortic Root Replacement in Destructive Endocarditis

open access: yesBrazilian Journal of Cardiovascular Surgery
Objective: To analyze patients’ preoperative characteristics, surgical data, postoperative courses, and short- and long-term outcomes after implantation of different full-root prostheses for destructive aortic valve endocarditis.
Marcin Szczechowicz   +5 more
doaj   +1 more source

The Ethics of Heterologous Ovarian Transplantation

open access: yes, 2023
This project examines the ethical permissibility of heterologous ovarian transplantation to treat infertility, ovarian insufficiency, or both. Based on currently available data regarding the procedures’ risks, outcomes, and alternatives, it argues that ...
Brundage, Janetta
core  

T Cell Repertoire Maturation Induced by Persistent and Latent Viral Infection Is Insufficient to Induce Costimulation Blockade Resistant Organ Allograft Rejection in Mice

open access: yesFrontiers in Immunology, 2018
CD28:CD80/86 pathway costimulation blockade (CoB) with the CD80/86-specific fusion protein CTLA4-Ig prevents T cell-mediated allograft rejection in mice.
Jaclyn R. Espinosa   +12 more
doaj   +1 more source

Induced Foxp3+ T cells colonising tolerated allografts exhibit the hypomethylation pattern typical of mature regulatory T cells.

open access: yesFrontiers in Immunology, 2016
Regulatory T cells expressing the transcription factor Foxp3 require acquisition of a specific hypomethylation pattern to ensure optimal functional commitment, limited lineage plasticity and long-term maintenance of tolerance.
Robert eHilbrands   +6 more
doaj   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

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