Results 61 to 70 of about 1,297,973 (324)

Long-term patency and complications of ringed polytetrafluoroethylene grafts used for middle hepatic vein reconstruction in living-donor liver transplantation

Korean Journal of Transplantation, 2020
Background : Homologous vein allografts are adequate for reconstruction of the middle hepatic vein (MHV) in living-donor liver transplantation (LDLT). However, supply is a matter of concern. To replace homologous vein allografts, polytetrafluoroethylene (
I-Ji Jung, Shin Hwang, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Chul-Soo Ahn, Deok-Bog Moon, Ki-Hun Kim, Gil-Chun Park, Young-In Yoon, Yo-Han Park, Hui-Dong Cho, Jae-Hyun Kwon, Yong-Kyu Chung, Sang-Hyun Kang, Sung-Gyu Lee   +15 more
doaj   +1 more source

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

Advanced Science, EarlyView.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang, Jianxin Fu, Tiandan Long, Chao Zhang, Fuhua Fan, Zhaobo Lang, Jian‐Kang Zhu   +6 more
wiley   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Embryonic Cell Grafts in a Culture Model of Spinal Cord Lesion: Neuronal Relay Formation is Essential for Functional Regeneration

Frontiers in Cellular Neuroscience, 2016
Presently there exists no cure for spinal cord injury. However, transplantation of embryonic tissue into spinal cord lesions resulted in axon outgrowth across the lesion site and some functional recovery, fostering hope for future stem cell therapies ...
Anne Tscherter, Martina Heidemann, Sonja Kleinlogel, Jürg Streit   +3 more
doaj   +1 more source

Homologous transplantation of fluorescently labelled enriched buffalo (Bubalus bubalis) spermatogonial stem cells to prepubertal recipients

Indian Journal of Animal Sciences, 2020
Spermatogonial stem cell transplantation provides a unique opportunity to study the biology of spermatogenesis and also offers an alternative approach for genetic modification in large animals.
A SHARMA, A KUMARESAN, N NALA, M TIWARI, M ROSHAN, M K SINGH, P PALTA, S K SINGLA, R S MANIK, M S CHAUHAN   +9 more
doaj   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

Advanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao, Yifu Shen, Zhihui Xiao, Zhenbo Han, Xu Liu, Ao Cai, Yanan Tian, Guang Lian, Wenya Ma, Yining Liu, Rui Gong, Hanjing Li, Xiuxiu Wang, Zhongyu Ren, Naufal Zagidullin, Lei Yu, Ye Tian, Yu Liu, Zhenwei Pan, Baofeng Yang, Benzhi Cai   +20 more
wiley   +1 more source

Cold ischemia or topical-ECMO for lung preservation: a randomized experimental study

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Lung preservation remains a challenging issue for lung transplantation groups. Along with the development of ex vivo lung perfusion, a new preservation method known as topical-ECMO (extracorporal membrane oxygenation) has been ...
Alessandro Wasum Mariani, Israel Lopes Medeiros, Paulo Manuel Pego-Fernandes, Flavio Guimaraes Fernandes, Fernando Do Vale Unterpertinguer, Lucas Matos Fernandes, Paulo Francisco Cardoso, Mauro Canzian, Fabio Biscegli Jatene   +8 more
doaj   +1 more source

Inhibitory effect of rapamycin-deep eutectic solvent eye drops on corneal allograft rejection in mice and its mechanism [PDF]

精准医学杂志
Objective To investigate the inhibitory effect of rapamycin (RAPA)-deep eutectic solvent (DES) eye drops on corneal allograft rejection in mice and its mechanism.
YANG Yang, HUANG Cixin, ZENG Fanxing, SUN Yaru, WEI Chao, WANG Hongwei, GAO Hua
doaj   +1 more source

Pregnancy following homologous prepubertal ovarian transplantation in the dog [PDF]

Journal of Experimental & Clinical Assisted Reproduction, 2008
In several canine models of hereditary human disease the homozygote dogs die prior to puberty, or have substantially reduced fertility. To create a clinically healthy animal that can be bred, but can also transmit the gene of interest, a model of homologous ovarian transplantation in prepubertal dogs was developed.
Jennifer K Pullium, Jennifer K Pullium, Ross Milner, Gary A Tuma   +3 more
openaire   +3 more sources

A Nonpolymorphic Class I Gene in the Murine Major Histocompatibility Complex [PDF]

, 1984
DNA sequence analysis of a class I gene (QlO), which maps to the Qa2,3 locus in the C57BL/lO (H- 2b haplotype) mouse, reveals that it is almost identical to a cDNA clone (pH16) isolated from a SWR/J (H-2q haplotype) mouse liver cDNA library.
Flavell, Richard A., Jay, Gilbert, Kress, Michael, Mellor, Andrew L., Weiss, Elisabeth H.   +4 more
core   +1 more source