Results 61 to 70 of about 1,296,795 (347)

MEDIMP: 3D Medical Images with clinical Prompts from limited tabular data for renal transplantation [PDF]

arXiv, 2023
Renal transplantation emerges as the most effective solution for end-stage renal disease. Occurring from complex causes, a substantial risk of transplant chronic dysfunction persists and may lead to graft loss. Medical imaging plays a substantial role in renal transplant monitoring in clinical practice. However, graft supervision is multi-disciplinary,
arxiv  

Electrocardiographic Studies in Homologous Canine Heart Transplantations [PDF]

Circulation Research, 1965
1) In a series of ten dogs subjected to heart transplantation, serial electrocardiograms were recorded from the transplanted and the recipient hearts. 2) Approximately one week following transplantation, changes appeared in the S-T segment and the T wave of the electrocardiogram of the recipient heart without significant alteration of the QRS
George E. Burch, Nicholas P. DePasquale, Edgar Pena, Keith Reemtsma   +3 more
openaire   +3 more sources

Rare surfactant‐related variants in familial and sporadic pulmonary fibrosis

Human Mutation, Volume 43, Issue 12, Page 2091-2101, December 2022., 2022
Abstract The role of constitutional genetic defects in idiopathic pulmonary fibrosis (IPF) is increasingly appreciated. Monogenic disorders associated with IPF affect two pathways: telomere maintenance, accounting for approximately 10% of all patients with IPF, and surfactant biology, responsible for 1%–3% of cases and often co‐occurring with lung ...
Rachel M. Sutton, Humberto Trejo Bittar, Daniel I. Sullivan, Agustin Gil Silva, Harinath Bahudhanapati, Anishka H. Parikh, Yingze Zhang, Kevin Gibson, John F. McDyer, Daniel J. Kass, Jonathan K. Alder   +10 more
wiley   +1 more source

Cases report and diagnosis and treatment of passenger lymphocyte syndrome after liver and renal transplantation

Zhongguo shuxue zazhi
Objective To summarize the clinical features, serological features, blood transfusion protocols and treatment of 3 cases of passenger lymphocyte syndrome(PLS) after ABO-incompatibility liver and renal transplantation in our hospital, in order to provide ...
Yuxin HE, Yiran MA, Shuang ZHANG, Jingchun JIN   +3 more
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Gut microbiota‐stem cell niche crosstalk: A new territory for maintaining intestinal homeostasis

iMeta, Volume 1, Issue 4, December 2022., 2022
Intestinal stem cells (ISCs) are protected by their niche and are regulated by Wnt, bone morphogenetic protein, and Notch. ISCs and their relationship with intestinal microbiota provide a feasible pathway to alleviate intestinal diseases. Diverse bacteria‐related postbiotics regulate ISCs and maintain their homeostasis.
Ning Ma, Xiyue Chen, Lee J. Johnston, Xi Ma   +3 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Molecular mechanisms, physiological roles, and therapeutic implications of ion fluxes in bone cells: Emphasis on the cation‐Cl− cotransporters

Journal of Cellular Physiology, Volume 237, Issue 12, Page 4356-4368, December 2022., 2022
Ion transport systems in the membranes of osteoblasts and osteoclasts play a key role in bone remodeling by coordinating the movement of Ca2+, PO42−, and H+ ions in and out of the osseous matrix. Based on the evidence available, the cation‐Cl− cotransporters could act as unexpectedly important players in this regard.
Alexandre P. Garneau, Samira Slimani, Ludwig Haydock, Thy‐René Nsimba‐Batomene, Florence C.M. Préfontaine, Mathilde M. Lavoie, Laurence E. Tremblay, Marie‐Jeanne Fiola, Fabrice Mac‐Way, Paul Isenring   +9 more
wiley   +1 more source

Impact of stem cell source on allogeneic stem cell transplantation outcome in hematological malignancies [PDF]

Vojnosanitetski Pregled, 2011
Background/Aim. Peripheral blood (PB) is used more frequently as a source of stem cells (SCs) for allogeneic transplantation. However, the influence of cell source on the clinical outcome of SC transplantation is not yet well established.
Stamatović Dragana, Balint Bela, Tukić Ljiljana, Elez Marija, Tarabar Olivera, Todorović Milena, Ostojić Gordana, Tatomirović Zeljka, Ljubenov Marika, Marjanović Slobodan, Malešević Milomir   +10 more
doaj   +1 more source

Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]

arXiv, 2023
While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv