Results 1 to 10 of about 18,682 (303)
Cell Transplantation, 2023 Organ transplantation is a highly utilized treatment for many medical conditions, yet the number of patients waiting for organs far exceeds the number available.
Jennifer L. Brown +3 more
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Blastocyst complementation: current progress and future directions in xenogeneic organogenesis [PDF]
Stem Cell Research & TherapyThe generation of organs derived from pluripotent stem cells can be achieved in vivo through the blastocyst complementation technique. This method is based on the introduction of pluripotent stem cells into organogenesis-disabled pre-implantation embryos,
Paula Barlabé +2 more
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Allogeneic hematopoietic stem cell transplantation for the treatment of chronic active Epstein–Barr virus infection [PDF]
Cell TransplantationChronic active Epstein–Barr virus (CAEBV) infection is a rare and highly lethal lymphoproliferative disorder. The pathological basis of this condition involves Epstein–Barr virus (EBV) persisting in hematopoietic stem cells, driving clonal expansion of T
Yu Wang +3 more
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PLoS ONE, 2022 The loss of functional cells through immunological rejection after transplantation reduces the efficacy of regenerative therapies for cardiac failure that use allogeneic induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs).
Shohei Yoshida +9 more
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Haematopoietic Chimera in Man After Allogenic (Homologous) Bone-marrow Transplantation [PDF]
BMJ: British Medical Journal, 1963 G. Mathe +4 more
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Frontiers in Cell and Developmental Biology, 2023 Millions of people suffer from end-stage refractory diseases. The ideal treatment option for terminally ill patients is organ transplantation. However, donor organs are in absolute shortage, and sadly, most patients die while waiting for a donor organ ...
Hemanta Sarmah +7 more
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Temporal chimeras produced by hypothalamic transplants [PDF]
The Journal of Neuroscience, 1992 The expression of locomotor activity by golden hamsters is temporally controlled by circadian oscillators contained within the suprachiasmatic nuclei. A genetic mutation has been found that alters the freerunning period of the locomotor activity rhythm from the wild- type value of approximately 24 to approximately 20 hr in homozygous mutants.
M A, Vogelbaum, M, Menaker
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Effect of angiotensin II type 2 receptor-interacting protein on adipose tissue function via modulation of macrophage polarization. [PDF]
PLoS ONE, 2013 We demonstrated that angiotensin II type 2 (AT2) receptor-interacting protein (ATIP) 1 ameliorates inflammation-mediated vascular remodeling independent of the AT2 receptor, leading us to explore the possibility of whether ATIP1 could exert anti ...
Fei Jing +8 more
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Tissue Targeted Embryonic Chimeras: Zebrafish Gastrula Cell Transplantation [PDF]
Journal of Visualized Experiments, 2009 Certain fundamental questions in the field of developmental biology can only be answered when cells are placed in novel environments or when small groups of cells in a larger context are altered. Watching how one cell interacts with and behaves in a unique environment is essential to characterizing cell functions.
Deschene, Elizabeth R. +1 more
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Communications Biology, 2023 Zebrafish (Danio rerio) is a commonly-used vertebrate model species for many research areas. However, its low milt volume limits effective cryopreservation of sperm from a single individual and often precludes dividing a single semen sample to conduct ...
Rigolin Nayak +3 more
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