Results 111 to 120 of about 49,168 (311)

Oral mucosal lesions in Polish patients with acute myeloid leukemia after allogeneic hematopoietic cell transplantation

Scientific Reports
The number of allogeneic hematopoietic cell transplantation constantly increases. Therefore, there is an urgent need to carefully analyze the general and oral health state of people with acute myeloid leukemia who underwent this procedure.
Aleksandra Wysocka-Słowik, Zuzanna Ślebioda, Barbara Dorocka-Bobkowska, Marzena Liliana Wyganowska   +3 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Allogeneic Transplantation for Relapsed Waldenström Macroglobulinemia and Lymphoplasmacytic Lymphoma

, 2017
Waldenstrom macroglobulinemia/lymphoplasmacytic lymphoma (WM/LPL) is characterized by lymphoplasmacytic proliferation, lymph node and spleen enlargement, bone marrow involvement, and IgM production.
David I. Marks, Kindwall-Keller, Tamila,, Veronika Bachanova, Woo-Ahn, Kwang,, Al-Homsi, A. Samer,, Mark, Tomer,, Taiga Nishihori, Hildebrandt, Gerhard,, Marks, David I.,, Siddhartha Ganguly, Chhabra, Saurabh,, Usmani, Saad,, Martens, Michael,, Vesole, David H.,, Michael Martens, Yago Nieto, Cornell, Robert F.,, Mohamed Kharfan-Dabaja, Gerhard Hildebrandt, Bachanova, Veronika,, Parameswaran Hari, Robert Peter Gale, Jiaxing Huang, Huang, Jiaxing,, Tamila Kindwall-Keller, Jean Yared, Ganguly, Siddhartha,, Saad Usmani, Hari, Parameswaran,, Cesar O. Freytes, David H. Vesole, Richard F. Olsson, Kamble, Rammurti T.,, Olsson, Richard F.,, Lazarus, Hillard M.,, A. Samer Al-Homsi, Ayman Saad, Kharfan-Dabaja, Mohamed,, Freytes, Cesar O.,, D'Souza, Anita,, Anita D'Souza, Mehdi Hamadani, Edward Copelan, Robert F. Cornell, Tomer Mark, Yared, Jean,, Kwang Woo-Ahn, Miguel-Angel Diaz, Saurabh Chhabra, Rammurti T. Kamble, Copelan, Edward,, Nieto, Yago,, Gale, Robert Peter,, Nishihori, Taiga,, Diaz, Miguel-Angel,, Hamadani, Mehdi,, Hillard M. Lazarus, Saad, Ayman,   +57 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Assessment of Nurses’ Performance Regarding Chemotherapy for Children Undergoing Conditioning Regimen Stem Cells Transplantation [PDF]

Tanta Scientific Nursing Journal
Background: Stem cells transplantation is a widely recognized treatment option for damaged or diseased bone marrow. High qualified nurses play a pivotal role in administration chemotherapy using standardized protocols during the conditioning phase.
Marwa Elden Eldeeb, Rahma Bahgat, Amal Younis   +2 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Long-Term Outcome after Bone Marrow Transplantation for Aplastic Anemia Using Cyclophosphamide and Total Lymphoid Irradiation as Conditioning Regimen

, 2008
We retrospectively studied 49 patients in a single institute to evaluate the long-term outcome of total lymphoid irradiation (TLI) conditioning for allogeneic stem cell transplantation (allo-SCT) to treat aplastic anemia (AA).
Kuwatsuka, Yachiyo, Suzuki, Ritsuro, Takahashi, Taro, Sugimoto, Kyoko, Ito, Masafumi, Miyamura, Koichi, Kodera, Yoshihisa, Inamoto, Yoshihiro, Murata, Makoto, Oba, Taku, Atsuta, Yoshiko, Yasuda, Takahiko, Tsujimura, Akane, Terakura, Seitaro   +13 more
core   +1 more source

Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics

Current Therapeutic Research
: Objectives: Treatment with tacrolimus requires strict control of the whole-blood concentration in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT).
Haruno Oku, BS, Saki Yoshida, BS, Takumi Hotta, BS, Hirohito Muroi, BS, Keizo Fukushima, PhD, Kei Irie, PhD, Tatsuya Hirano, BS, Yoshimitsu Shimomura, MD, Takayuki Ishikawa, MD, PhD, Hiroaki Ikesue, PhD, Nobuyuki Muroi, PhD, Tohru Hashida, PhD, Nobuyuki Sugioka, PhD   +12 more
doaj   +1 more source