Results 111 to 120 of about 655,517 (311)

Qualitative and quantitative polymerase chain reaction monitoring of minimal residual disease in relapsed chronic lymphocytic leukemia: early assessment can predict long-term outcome after reduced intensity allogeneic transplantation

Haematologica, 2009
Background The graft-versus-leukemia effect is able to induce clinical responses in patients with chronic lymphocytic leukemia treated with a reduced intensity conditioning regimen, followed by allogeneic stem cell transplantation.
Lucia Farina, Cristiana Carniti, Anna Dodero, Antonio Vendramin, Anna Raganato, Francesco Spina, Francesca Patriarca, Franco Narni, Fabio Benedetti, Attilio Olivieri, Paolo Corradini   +10 more
doaj   +1 more source

Amygdala-hippocampal involvement in human aversive trace conditioning revealed through event-related functional magnetic resonance imaging [PDF]

, 1999
Previous functional neuroimaging studies have characterized brain systems mediating associative learning using classical delay conditioning paradigms.
Buchel, C, Friston, K., Armony, J., Armony, J, Dolan, R, Dolan, R. ; https://orcid.org/, Buchel, C., Friston, K   +7 more
core  

Bone Marrow Transplantation for Fanconi Anemia Using Fludarabine-Based Conditioning [PDF]

, 2011
In the mid-1990s, we introduced a fludarabine (Flu)-based conditioning regimen for hematopoietic stem cell transplantation (HSCT) in patients with Fanconi anemia (FA).The aim of this study is to compare Flu-based conditioning to alternative regimens in ...
Alexey Maschan, Dmitry Balashov, Rebecca Brooks, Or, Reuven, Weintraub, Michael, Jerry Stein, Stepensky, Polina, Resnick, Igor B., Trakhtman, Pavel, Lyudmila Rheingold, Shapira, Michael Y., Revel-Vilk, Shoshana, Balashov, Dmitry, Skorobogatova, Elena, Igor B. Resnick, Brooks, Rebecca, Rheingold, Lyudmila, Pavel Trakhtman, Elena Skorobogatova, Shoshana Revel-Vilk, Stein, Jerry, Maschan, Alexey, Polina Stepensky, Michael Y. Shapira, Michael Weintraub, Reuven Or   +25 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effect of acute and chronic GVHD on relapse and survival after reduced-intensity conditioning allogeneic transplantation for myeloma [PDF]

, 2012
We evaluated the effect of acute and chronic GVHD on relapse and survival after allogeneic hematopoietic SCT (HSCT) for multiple myeloma using non-myeloablative conditioning (NMA) and reduced-intensity conditioning (RIC).
Gupta, V., Meehan, K., Shrestha, S., Silva, G. T. da, Gale, R. P., Dispenzieri, A., McCarthy, P., Lonial, S., Kamble, R., Lazarus, H., Remberger, M., Freytes, C. O., Gibson, J., Zhang, M-J, Holmberg, L., Hari, P. N., Ringden, O., Schouten, H., Milone, G. A.   +18 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Oral mucosal lesions in Polish patients with acute myeloid leukemia after allogeneic hematopoietic cell transplantation

Scientific Reports
The number of allogeneic hematopoietic cell transplantation constantly increases. Therefore, there is an urgent need to carefully analyze the general and oral health state of people with acute myeloid leukemia who underwent this procedure.
Aleksandra Wysocka-Słowik, Zuzanna Ślebioda, Barbara Dorocka-Bobkowska, Marzena Liliana Wyganowska   +3 more
doaj   +1 more source

The Emerging Role of Gemcitabine in Conditioning Regimens for Hematopoietic Stem Cell Transplantation [PDF]

, 2014
The specific combination for conditioning regimens in hematopoietic stem cell transplantation continues to be a premier area of focus in research.
Nieto, Yago, Hart, James W., Wang, Emily, Gulbis, Alison   +3 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Curing autoimmune diabetes in mice with islet and hematopoietic cell transplantation after CD117 antibody-based conditioning

The Journal of Clinical Investigation
Mixed hematopoietic chimerism after allogeneic hematopoietic cell transplantation (HCT) promotes tolerance of transplanted donor-matched solid organs, corrects autoimmunity, and could transform therapeutic strategies for autoimmune type 1 diabetes (T1D).
Preksha Bhagchandani, Stephan A. Ramos, Bianca Rodriguez, Xueying Gu, Shiva Pathak, Yuqi Zhou, Yujin Moon, Nadia Nourin, Charles A. Chang, Jessica Poyser, Brenda J. Velasco, Weichen Zhao, Hye-Sook Kwon, Richard Rodriguez, Diego M. Burgos, Mario A. Miranda, Everett Meyer, Judith A. Shizuru, Seung K. Kim   +18 more
doaj   +1 more source