Results 71 to 80 of about 4,786,268 (341)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation [PDF]

, 2008
Hematopoietic stem cell transplantation (HSCT) requires conditioning treatments such as irradiation, which leads to a severely delayed recovery of T cell immunity and constitutes a major complication of this therapy.
Boyd, R. L., Gill, J. W., Holländer, G. A., Kenins, L., Wodnar-Filipowicz, A.   +4 more
core   +3 more sources

Decitabine-Containing Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Intermediate- and High-Risk Myelodysplastic Syndrome/Acute Myeloid Leukemia: Potential Decrease in the Incidence of Acute Graft versus Host Disease

Cancer Management and Research, 2019
Qing Ya Wang,* Yuan Li,* Ze Yin Liang, Yue Yin, Wei Liu, Qian Wang, Yu Jun Dong, Yu Hua Sun, Wei Lin Xu, Han Yun Ren Department of Hematology, Peking University First Hospital, Peking University, Beijing, People’s Republic of China*These authors ...
Wang QY, Li Y, Liang ZY, Yin Y, Liu W, Wang Q, Dong YJ, Sun YH, Xu WL, Ren HY   +9 more
doaj  

Competing-risk outcomes after hematopoietic stem cell transplantation from the perspective of time-dependent effects

Haematologica, 2018
The success of hematopoietic stem cell transplantation is determined by multiple factors. Additional complexity is conferred by covariables showing time-dependent effects.
Daniel Fuerst, Sandra Frank, Carlheinz Mueller, Dietrich W Beelen, Johannes Schetelig, Dietger Niederwieser, Jürgen Finke, Donald Bunjes, Nicolaus Kröger, Christine Neuchel, Chrysanthi Tsamadou, Hubert Schrezenmeier, Jan Beyersmann, Joannis Mytilineos   +13 more
doaj   +1 more source

Experiences of allogeneic hematopoietic cell transplantation following non-myeloablative conditioning regimen in severely comorbid patients with myelofibrosis: case series with a patient presenting with extensive extramedullary hematopoiesis

Therapeutic Advances in Hematology, 2020
We have performed allogeneic hematopoietic cell transplantation (allo-HCT) using a reduced intensity conditioning regimen for curative management of advanced myelofibrosis (MF).
Jae-Ho Yoon, Sung-Soo Park, Gi June Min, Silvia Park, Sung-Eun Lee, Byung-Sik Cho, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Chang-Ki Min, Seok-Goo Cho, Jong Wook Lee, Ki-Seong Eom   +12 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Functional immune reconstitution after allogeneic hematopoietic stem cell transplantation in myeloablative and non-myeloablative conditioned patients

Scientific Reports
Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a treatment modality for several hematological and immune-driven diseases. A conditioning regimen precedes transplantation.
Patrick Terrence Brooks, Lia Minculescu, Rebecca Svanberg Teglgaard, Hans Jakob Hartling, Jose Antonio Salado-Jimena, Lone Smidstrup Friis, Brian Kornblit, Ida Schjødt, Søren Lykke Petersen, Niels Smedegaard Andersen, Susanne Dam Nielsen, Jens Lundgren, Hanne Vibeke Marquart, Lars Klingen Gjaerde, Henrik Sengeløv, Sisse Rye Ostrowski   +15 more
doaj   +1 more source

Reduced intensity conditioning allogeneic stem cell transplantation for adult patients with acute lymphoblastic leukemia: a retrospective study from the European Group for Blood and Marrow Transplantation

Haematologica, 2008
This retrospective study reported the outcome of 97 adult acute lymphoblastic leukemia patients who received a reduced-intensity conditioning allogeneic stem cell transplantation.
Mohamad Mohty, Myriam Labopin, Reza Tabrizzi, Niklas Theorin, Axel A Fauser, Alessandro Rambaldi, Johan Maertens, Shimon Slavin, Ignazio Majolino, Arnon Nagler, Didier Blaise, Vanderson Rocha   +11 more
doaj   +1 more source

An Experience of Donor Lymphocyte Infusion after Reduced-Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease [PDF]

, 2020
Tahereh Rostami, Azadeh Kiumarsi
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source