Results 101 to 110 of about 587,692 (337)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Transplantes em notícia: um jornalismo delineado em factos declinados por fontes oficiais [PDF]

, 2012
Em 2011, o problema dos transplantes foi um tópico que suscitou bastante atenção mediática, constituindo-se como um assunto algo recorrente, comparado com anos anteriores.
Fernandes, Luciana Gabriela Moura, Gomes, Emiliana Sofia Coelho, Lopes, Felisbela, Marinho, Sandra, Ruão, Teresa   +4 more
core   +1 more source

Abusive drinking after liver transplantation is associated with allograft loss and advanced allograft fibrosis [PDF]

, 2013
John P. Rice, Jens C. Eickhoff, Rashmi Agni, Aiman Ghufran, Rinjal Brahmbhatt, Michael R. Lucey   +5 more
openalex   +1 more source

Erectile dysfunction in patients after kidney transplantation and nephrectomy in living donors: literature review

, 2023
З. А. Кадыров, A. Yu. Odilov, F. S. Sadulloev, M.V. Faniev, S. I. Suleymanov, E. I. Rossoshanskaya   +5 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Aplicação de Membranas Amnióticas na Reconstrução da Superfície Ocular Externa em Idade Pediátrica [PDF]

, 2016
Introdução: Vários estudos comprovam os benefícios da aplicação de membranas amnióticas na reconstrução da superfície ocular em idade adulta, pelos seus efeitos anti-inflamatorios, anti-adesivos e anti-apoptóticos.
Basílio, AL, Candelária, P, Cardigos, J, Crisóstomo, S, Maduro, V, Proença, R, Toscano, A   +6 more
core  

Deliberate donation of umbilical cord blood in the University Hospital Virgen de la Arrixaca (2010-2011). Current situation and influences of the obstetrical-foetal variables [PDF]

, 2012
Objetivos: A principios de 2010 el Hospital Universitario Virgen de la Arrixaca puso en marcha, en el servicio de partos, el protocolo de donación voluntaria de sangre de cordón umbilical (SCU).
Martínez Rojo, Carmen, Martínez Román, Concepción, Morillas Guijarro, Daniel, Rodríguez Portilla, Natalia Emilia, Soto Herrero, Verónica   +4 more
core   +1 more source

Successes and Failures of Stem Cell Transplantation in Autoimmune Diseases [PDF]

, 2011
Alan Tyndall
openalex   +1 more source

Process control: simply a matter of efficiency or of survival and costs? A single-centre quality improvement project in living donor renal transplant [PDF]

, 2023
Filippo Paoletti, Giorgio Vittori, Adel Jaser, Natalia Romina Zanoni, Walter Ricciardi, Franco Citterio, Antonio Giulio de Belvis   +6 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source