Results 91 to 100 of about 5,891 (253)

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Desigualdades por sexo e por raça e o direito aos transplantes de órgãos no Brasil

, 2012
O presente texto trata do perfi l dos transplantados e do problema das desigualdades no acesso aos transplantes de órgãos no Sistema Nacional de Transplantes (SNT) do Sistema Único de Saúde (SUS).
MARINHO, Alexandre, ALMEIDA, Vivian Vicente de, CARDOSO, Simone de Souza   +2 more
core   +1 more source

USO DE VENETOCLAX EM COMBINAÇÃO COM R-CHOP NO MANEJO DA TRANSFORMAÇÃO DE RICHTER: RELATO DE CASO

Hematology, Transfusion and Cell Therapy
Introdução: A transformação de Richter (TR) é caracterizada pelo desenvolvimento de um linfoma agressivo em pacientes com diagnóstico prévio ou simultâneo de Leucemia Linfocítica Crônica (LLC) ou Linfoma Linfocítico de Pequenas Células.
JA Gomes, FM Marques, LQ Marques, DSC Filho, MS Pastori, KP Melillo, LLM Perobelli   +6 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

SÍNDROME DE POEMS - UMA CAUSA INCOMUM DE PLAQUETOSE

Hematology, Transfusion and Cell Therapy
Introdução: A síndrome de POEMS é uma rara manifestação paraneoplásica relacionada à doença clonal plasmocitária. O acrônimo representa alguns dos componentes da síndrome: polineuropatia, organomegalia, endocrinopatia, pico monoclonal e alterações ...
JA Gomes, JO Martins, LQ Marques, DSC Filho, MS Pastori, FM Marques, KP Melillo, LLM Perobelli   +7 more
doaj   +1 more source

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

DESAFIOS NO TRATAMENTO DE SEGUNDA LINHA DE LEUCEMIA LINFOCÍTICA CRÔNICA: EXPERIÊNCIA DE UM SERVIÇO PÚBLICO BRASILEIRO

Hematology, Transfusion and Cell Therapy
Introdução: Apesar dos avanços das terapias-alvo nas últimas décadas, o tratamento da Leucemia Linfocítica Crônica (LLC) recaída/refratária no Brasil continua sendo um desafio significativo, especialmente no contexto do sistema de saúde pública.
FM Marques, EM Oshiro, AA Barroso, FS Azevedo, KP Melillo, LLM Perobelli   +5 more
doaj   +1 more source