Results 81 to 90 of about 4,724 (304)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2010 Transplantes de Quercus suber realizados en Huelva en mayo-junio de ...
Martín Bolaños, Manuel
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Estratégias de enfrentamento da enfermagem no cuidado ao potencial doador de órgãos [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2010Trata-se de uma pesquisa qualitativa exploratória, descritiva, cujo objetivo foi compreender as ...
Souza, Silvia Silva
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A Impossibilidade de “Transplantes Jurídicos”
, 2014 A IMPOSSIBILIDADE DE “TRANSPLANTES JURÍDICOS”THE IMPOSSIBILITY OF ‘LEGAL TRANSPLANTS’Pierre LegrandRESUMO: Há muitos anos, uma grande quantidade dos estudos de direito comparado tem sido baseada na metáfora dos “transplantes jurídicos”.
Pierre Legrand, Legrand, Pierre
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Identificação e notificação de doadores de órgão e tecidos em terapia intesiva [PDF]
, 2004 Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Silva, Juliany Nascimento
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Transplantes de órgãos sólidos no Brasil: Uma revisão narrativa
, 2019 De acordo com a Organização Mundial da Saúde (OMS), transplante é a transferência compatível de células humanas, tecidos ou órgãos de um doador para um receptor, visando recuperar a atividade do órgão comprometido. Nesse cenário, o presente artigo visa
Santos, Isabelle Pontes dos
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source