Results 131 to 140 of about 3,354,548 (316)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Unijna polityka w zakresie zewnętrznych stosunków w dziedzinie lotnictwa [PDF]

internetowy Kwartalnik Antymonopolowy i Regulacyjny, 2016
Artykuł dotyczy unijnej polityki w zakresie zewnętrznych stosunków w dziedzinie lotnictwa. Autor przedstawia jej genezę, w tym prawne i ekonomiczno-polityczne implikacje orzeczeń Europejskiego Trybunału Sprawiedliwości z dnia 5 listopada 2002 r.
Marian Bujnowski
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Differences in transport and land use in thirteen comparable Australian, American, Canadian and European cities between 1995/6 to 2005/6 and their implications for more sustainable transport

, 2011
This paper summarises the findings of thirteen comparable North American, Australian and European cities in relation to a range of transport and land use-related indicators and their changes between 1995/96 and 2005/06.
Kenworthy, Jeffrey, Inbakaran, Christina
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Les systèmes de transport pour penser l’insularité : regards croisés entre la Nouvelle-Calédonie et le Vanuatu

Espace populations sociétés
For some geographers, isolation and insularity are linked, so transport systems must compensate for the effects of insularity. Under these conditions, can transport systems open a new path to understanding insularity?
Anne-Clémence Duverger
doaj   +1 more source

CURRENT CHALLENGES IN THE ECONOMICS OF TRANSPORT SYSTEMS – a stakeholder and club good approach

, 2012
In this article, after discussing the concept of transport systems and the importance of its sustainability, stakeholder theory and club good theory are presented as useful instruments for analyzing different challenges for the sustainability of ...
Platje, Joost; International University of Logistics and Transport
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

How does negative triangularity mitigate ITG turbulence and transport?

Nuclear Fusion
Improved confinement in negative triangularity (NT) experiments is attributed to reduced fluxes driven by micro-turbulence. The physical mechanism of why thermal confinement improves in NT relative to PT is unknown.
Rameswar Singh, P.H. Diamond, A. Marinoni   +2 more
doaj   +1 more source

Understanding air pollution transport

, 2002
Electronic data.; Title from PDF cover (viewed Aug. 11, 2006).; "2002 Ozone Transport Commission Annual Meeting, OTC Modeling Committee-Transport Workgroup."; "August 6, 2002."; Powerpoint ...
Underhill, Jeffrey.
core