Results 131 to 140 of about 3,358,728 (316)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
What impact do EU environmental policies have on urban transport? [PDF]
Urban transport policy is shaped by multiple factors. It can be influenced by local, regional, national or supranational actors. The role of the European Union in initiating urban transport policies is unclear and its impact little understood.
Cavoli, CM
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Unijna polityka w zakresie zewnętrznych stosunków w dziedzinie lotnictwa [PDF]
Artykuł dotyczy unijnej polityki w zakresie zewnętrznych stosunków w dziedzinie lotnictwa. Autor przedstawia jej genezę, w tym prawne i ekonomiczno-polityczne implikacje orzeczeń Europejskiego Trybunału Sprawiedliwości z dnia 5 listopada 2002 r.
Marian Bujnowski
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Can TERM determine the environmental impact of transport? - Reflections on a core set of transport indicators [PDF]
This paper systematically reviews two questions central for environmental im-pact assessment: What are the relevant environmental impacts of transport? And, are they improving, i.e. what is their overall assessment?
Borken, Jens
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Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Towards a national vision for a secure, connected future through Cooperative Connected Transport Systems (C-ITS) [PDF]
Cooperative Intelligent Transport Systems (C-ITS) enable real-time wireless communication between vehicles, roadside infrastructure, mobile devices and back-office systems. They have been developed as a way to deliver a safer and more efficient transport
Transport Certification Australia
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For some geographers, isolation and insularity are linked, so transport systems must compensate for the effects of insularity. Under these conditions, can transport systems open a new path to understanding insularity?
Anne-Clémence Duverger
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Changes in the interpretation of logistics and transport issues in UE policy [PDF]
At the beginning of 21st century, UE issued a document in which, in accordance with Lisbon Strategy, basic aspects of UE transport policy were introduced.
Bujak, Andrzej; the International University of Logistics and Transport in Wrocław
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