Results 141 to 150 of about 3,354,548 (316)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Centralization and transport of critically ill pediatric patients
Frontiers in PediatricsBackgroundCaring for critically ill pediatric patients requires specialized expertise, centralized facilities, and efficient transport systems. The centralization of pediatric intensive care units in tertiary centers has enhanced clinical outcomes ...
Ryo Kamidani +3 more
doaj +1 more source
Statistics from the Department of Transport Welland Ship Canal
, 1937 Statistics from the Department of Transport on the Welland Ship ...
Department of Transport
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Benchmarking public transport accessibility in Australasian cities
, 2012 There is growing recognition by all tiers of government that transformation of the public transport system is necessary if it is to offer a real alternative to car-based travel in Australasian cities.
Curtis, Carey, Scheurer, Jan
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Concept of Freight Road-Railing Transport in Bimodal Technology
, 2016 The article presents: the essence of bimodal transport, technical measures, technologies and setting bimodal trains in bimodal transport systems. Summary of the article is the analysis of advantages and disadvantages of road-rail freighttransport in ...
Mindur, Leszek; the International University of Logistics and Transport in Wrocław
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THE INNOVATIVE ACTIVITIES IMPROVING COMPETITIVENESS OF TRANSPORT COMPANIES
, 2022 The article refers to the challenges aimed at identifying decisions that translate into optimization in the TFL industry, on the example of selected activities of transport companies.
Wiśniewski, Grzegorz; The International University of Logistics and Transport in Wrocław
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Program for Modelling Queuing Systems in Transport
, 2012 This paper presents an example application of a software program developed using the programming language VBA and designed for modelling queuing systems in the field of transport.
Dimitrov, Stavri Dimitri; Todor Kableshkov University of Transport - Sofia
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