Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Mass Rapid Transit for Perth & Peel @ 3.5 Million and Beyond
, 2016 Research by the Planning and Transport Research Centre (PATREC) in Western Australia, commissioned by the State Government of Western Australia (WA), examined strategic directions for public mass rapid transit (MRT) to serve WA’s capital city Perth and ...
Planning and Transport Research Centre (PATREC)
core +2 more sources
INTERNATIONAL TRANSIT VIA THE NORTHERN SEA ROUTE: THREATS, OPPORTUNITIES, AND FUTURE PROSPECTS
Север и рынок: формирование экономического порядкаThe Northern Sea Route (NSR) is a historically significant transport corridor in Russia and a crucial component of the country’s national and economic security.
Anna B. Nikolaeva
doaj +1 more source
The essence and factors of development of transit potential of railway transport of Ukraine
Вісник економіки транспорту і промисловості, 2014 Trends of railway transport of Ukraine, accompanied by the constant fall in transit traffic and worsening financial and economic situation of railways, drew attention to the factors in the development of transit potential of the railway industry. This paper investigates the essence of the concept of " transit potential " and highlights the author's ...
openaire +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
Identifying Inaccessible Areas with Potential to Enhance Transit Market
, 2011 The focus of this manuscript is 1) to compute a transit accessibility index based on demographic/socio-economic characteristics and land use characteristics for each transit stop and route and the entire study area, and 2) identify inaccessible areas to ...
Pulugurtha, Srinivas S. +2 more
core +1 more source
The dark side of making transit irresistible: The example of France [PDF]
The French experience in developing policies to reduce car use in metropolitan areas is presented in this paper as an illustration of the lack of recognition of the broader set of criteria on which specific policy frameworks should be judged.
David A. Hensher, Dominique Bouf
core
FROM CENTRALITY TO INTERMEDIACY IN THE GLOBAL TRANSPORT NETWORK? UKRAINE’S TRIALS AND TRIBULATIONS AS A POTENTIAL TRANSIT COUNTRY [PDF]
Contemporary Economy, 2015 Ukraine currently is in a very complex economic and political situation, which in itself represents a pivotal point for its further recovery and evolution. Nevertheless, the rise of economic centres in Eastern and Central Europe creates opportunities for Ukraine to develop short sea shipping services (via the Black Sea) and water and land-based hub ...
Grushevska, Kateryna, Notteboom, Theo
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Transit and Trade Barriers in Eastern South Asia: A Review of the Transit Regime and Performance of Strategic Border-Crossings [PDF]
The analysis of this paper shows that a regional transit arrangement would perhaps enhance the regional trade, controlling for other variables. At the same time, implementation of e-governance at border is found to be significant determinant of trade ...
Sachin Chaturvedi +2 more
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