Results 121 to 130 of about 5,329 (286)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Mass Rapid Transit for Perth & Peel @ 3.5 Million and Beyond

, 2016
Research by the Planning and Transport Research Centre (PATREC) in Western Australia, commissioned by the State Government of Western Australia (WA), examined strategic directions for public mass rapid transit (MRT) to serve WA’s capital city Perth and ...
Planning and Transport Research Centre (PATREC)
core  

Assessment of a transport policy potential for intermodal mode shift on a European scale

, 2007
Policies of general nature for improving the competitive position of intermodal transport have not always been successful. On the contrary, specific policies, such as targeting the supply chain or the offered services and transport are probably more ...
Tsamboulas, D, Lekka, A-M, Lekka, Anna-Maria, Vrenken, H, Tsamboulas, Dimitrios, Vrenken, Huub   +5 more
core   +1 more source

Potential Users of River Transport Integrated with the South Sumatera Light Rail Transit (LRT) after Improvements to the Facilities in Accordance with Public Perception [PDF]

, 2023
Edi Kadarsa, Reini Silvia Ilmiaty, Apriansyah Putra   +2 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Flexing service schedules: Assessing the potential for demand-adaptive hybrid transit via a stated preference approach

, 2017
This paper assesses the demand for a flexible, demand-adaptive transit service, using the Chicago region as an example. We designed and implemented a stated-preference survey in order to (1) identify potential users of flexible transit, and (2) inform ...
Frei, Charlotte, Hyland, Michael, Mahmassani, Hani S.   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Life-Cycle Asset Management in Residential Developments Building on Transport System Critical Attributes via a Data-Mining Algorithm

Buildings, 2018
Public transport can discourage individual car usage as a life-cycle asset management strategy towards carbon neutrality. An effective public transport system contributes greatly to the wider goal of a sustainable built environment, provided the critical
Umair Hasan, Andrew Whyte, Hamad Al Jassmi   +2 more
doaj   +1 more source

Transit Costs and Cost Efficiency: Bootstrapping Nonparametric Frontiers. [PDF]

This paper explores a selection of recently proposed bootstrapping techniques to estimate non-parametric convex (DEA) cost frontiers and efficiency scores for transit firms.
Kristiaan Kerstens, Bruno De Borger, Matthias Staat   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source