Results 121 to 130 of about 61,913 (296)
E-scooter sharing (ESS) is an emerging shared micro-mobility that may enhance urban travel accessibility. This study investigates the potential of ESS used as the feeder to public transit to improve accessibility compared to sole public transit ...
Hu, Liyang, +9 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Landlockedness, Infrastructure and Trade:New Estimates for Central Asian Countries [PDF]
This paper assesses the impact of internal infrastructure and landlockedness on Central Asian trade. The impact of landlockedness on Central Asian’s trade costs is split into several components, using a panel gravity equation estimated on a large sample ...
Céline CARRERE, Christopher GRIGORIOU
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Prospects of Development of the Transit Function of Georgia under the Conditions of Globalization [PDF]
Ovidius University Annals: Economic Sciences Series, 2017 The purpose of our research is to analyze the effectiveness of transit potential of Georgia forthe sustainable development of the country's economy in terms of globalization and to evaluate therole of transport infrastructure in the field of transport ...
Kavtaradze Medea, Bejanidze Natia
doaj
Assessing Bike-Transit Accessibility
Bicycles are a potential first-last mile mode that can augment the service area of public transit, yet it is difficult to fully account for bike-to-transit trips in planning and travel demand modeling processes.
Guensler, Randall +2 more
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Attitudinal Study on a Reciprocal Community Transport System in Japan
, 2007 In Japan, some mass transit companies were withdrawn from bus services in local municipalities after deregulation in 2002. Elderly people without a driver\u27s license cannot help but depend on transport services provided by family members, a ...
Kishi, Kunihiro, Satoh, Keiichi
core +2 more sources
Trans-Caspian International Transport Route Infrastructure Assessment Using Simulation Modelling
Transport and TelecommunicationThe Trans-Caspian International Transport Route (TITR) is one of the main transport corridors between China and Europe. It passes through the territory of Kazakhstan, as well as the countries of the South Caucasus, Turkey, and Iran, and contributes to ...
Zhumanov Azat +2 more
doaj +1 more source