Results 131 to 140 of about 5,329 (286)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Экономика: стратегия и практика, 2019 The purpose of this research is to analyze the export potential of transport and logistics services, identify factors affecting exports and justify its development directions for Kazakhstan in order to increase the share of high-tech exports.In this ...
doaj
The dark side of making transit irresistible: The example of France [PDF]
The French experience in developing policies to reduce car use in metropolitan areas is presented in this paper as an illustration of the lack of recognition of the broader set of criteria on which specific policy frameworks should be judged.
David A. Hensher, Dominique Bouf
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
INTERNATIONAL TRANSIT VIA THE NORTHERN SEA ROUTE: THREATS, OPPORTUNITIES, AND FUTURE PROSPECTS
Север и рынок: формирование экономического порядкаThe Northern Sea Route (NSR) is a historically significant transport corridor in Russia and a crucial component of the country’s national and economic security.
Anna B. Nikolaeva
doaj +1 more source
Moravian Geographical Reports, 2016 Urban environments in post-socialist cities have generated new challenges for urban planners and decision makers. As one example, the transport infrastructure of Bratislava has not been adjusted with respect to increasing mobility and the transit ...
Ďurček Pavol, Horňák Marcel
doaj +1 more source
Assessing the Costs for Hybrid versus Regular Transit Buses, October 2012
, 2012 This technical brief summarizes information about the costs and benefits that have been attributed to use of hybrid transit buses as found in the literature.
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source