Results 131 to 140 of about 4,559,188 (330)
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Swarm intelligence in transportation engineering [PDF]
Gang Chen, Fang Zong
openaire +3 more sources
Forensic Engineering Analysis: Smoke Transport To Upper Floors During 1980 MGM Grand Hotel Fire
M. Meckler
openalex +1 more source
Report on 6th U.S.–Japan Joint Seminar on Nanoscale Transport Phenomena—Science and Engineering [PDF]
Theodorian Borca‐Tasciuc +24 more
openalex +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Coupling Geomechanics and Transport in Petroleum Engineering [PDF]
Maurice B. Dusseault
openalex +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source

