Results 21 to 30 of about 10,647 (213)

Statistical Analysis of Track Geometry Parameters on Tramway Line No. 1 in Budapest

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2022
The article examines the superstructures of the tramway tracks of tramway line No. 1 in Budapest (the capital of Hungary). Since the first appearance of tramways, several technological advancements have been made to serve passenger needs as efficiently ...
Vivien Jover, Szabolcs Fischer
doaj   +1 more source

Evolution of the Road Network Topology of Central European Housing Estates

open access: yesInfrastructures, 2023
The analysis of road network topology has attracted the attention of researchers in the past few decades. In this study, the road topology of housing estates in a few selected Central European countries (Hungary, Austria, Czech Republic, and Slovakia ...
Pál Hegyi, Attila Borsos, Csaba Koren
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

FEM Modelling Possibilities of Glued Insulated Rail Joints for CWR Tracks

open access: yesActa Technica Jaurinensis, 2020
In this paper the authors detail the possibilities of modelling of finite element method (FEM) of glued insulated rail joints which are applied in railway tracks with continuously welded rails (CWR).
Attila Németh   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Ws of MaaS: Understanding mobility as a service fromaliterature review

open access: yesIATSS Research, 2020
Transport integration has evolved into Mobility as a service (MaaS), and as a recent topic, MaaS-literature is rapidly growing. This study analyses 57 MaaS-focused documents (the majority being peer-reviewed articles) from Scopus in January 2019. The aim
Daniela Arias-Molinares   +1 more
doaj   +1 more source

Is the cubic parabola really the best railway transition curve?

open access: yesOpen Engineering, 2021
In the current study, the authors tested two railway transition curves in terms of their usefulness for railway practice. The first curve was a cubic parabola – the curve most popular in railway engineering.
Zboinski Krzysztof, Woznica Piotr
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

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