Results 81 to 90 of about 485,603 (310)

A generic communication architecture for end to end mobility management in the Internet [PDF]

open access: yes, 2007
The proliferation of laptops, cellular phones, and other mobile computing platforms connected to the Internet has triggered numerous research works into mobile networking.
Sénac, Patrick   +5 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

A cross-layer approach to enhance QoS for multimedia applications over satellite [PDF]

open access: yes, 2009
The need for on-demand QoS support for communications over satellite is of primary importance for distributed multimedia applications. This is particularly true for the return link which is often a bottleneck due to the large set of end-users accessing a
Exposito, Ernesto   +4 more
core   +1 more source

Transitory Master Key Transport Layer Security for WSNs

open access: yesIEEE Access, 2020
Security approaches in Wireless Sensor Networks (WSNs) are normally based on symmetric cryptography. Instead of symmetric encryption, some alternative approaches have been developed by using public-key cryptography. However, the higher computational cost
Mattia Griotti   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Electron Transport Layer for Efficient Hybrid Perovskite Solar Cells

open access: yes, 2015
A novel multifunctional inverse opal-like TiO2 electron transport layer (IOT-ETL) is designed to replace the traditional compact layer and mesoporous scaffold layer in perovskite solar cells (PSCs).
Yang, Shuang   +13 more
core   +1 more source

Knowledge Base for an Autonomic Transport Layer [PDF]

open access: yes, 2011
The accelerated development of Internet and mobile devices has lead to new QoS-demanding distributed applications and new QoS-providing communication services, particularly at the transport level. The diversity of transport services and underlying networks environments asks for a novel design of the transport layer, able to provide in a transparent and
Expósito, Ernesto   +2 more
openaire   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Boundary layer theory description of solute transport in soil

open access: yes, 2007
Solute transport through soil may affect groundwater and surface water quality. The convection-dispersion equation has been widely used to describe soil solute transport processes.
Wang, QJ (Wang, Quanjiu)   +2 more
core  

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