Results 101 to 110 of about 66,320 (342)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The Role of EU Transport Market Liberalization in Shaping Directions of Rail Energy Consumption Rationalization in Relation to the Export of Goods: The Case of Poland

open access: yesEnergies
This article discusses the impact of rail market liberalization on the energy intensity of rail in relation to the export of goods, as well as the identification of multidimensional cause-and-effect relationships between rail energy intensity and the ...
Elżbieta Szaruga   +4 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

LIABILITY OF THE TRANSPORTATOR IN THE CASE OF THE RAILWAY TRANSPORT CONTRACT [PDF]

open access: yesChallenges of the Knowledge Society, 2019
When dealing with rail transport, whether we deal with aspects of domestic or international rail transport, the provisions of GO no. 7/2005 for the approval of the Romanian Railways Regulation and the Romanian Rail Transport Regulations for Internal ...
Adriana Elena BELU
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Factors facilitating intermodal transport of perishable goods - transport purchasers viewpoint

open access: yesEuropean Transport / Trasporti Europei, 2011
The aim of this article is to identify factors that facilitate increased use of intermodal transport for perishable products based on a survey of firms exporting fresh fish from Norway to Continental Europe. The experiences in the Norwegian aquaculture industry indicate that intermodal transport solutions must be expanded and that the long haul by rail
Sandberg-Hanssen, Thor-Erik   +1 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Preconditions for Returning Highly-Profitable Shot Lots to Railway Transport

open access: yesВестник Российского экономического университета имени Г. В. Плеханова
The article describes reasons for transition of small shipments from railway transport to automobile one and studies proposals to return highly-profitable shot lots back to the railway transport. Today we can observe a rise in the volume of shot lots and
D. A. Bakunin   +2 more
doaj   +1 more source

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