Results 71 to 80 of about 963,265 (263)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

An eCertificate Program in Transportation Planning [PDF]

open access: yes
DTRT06-G-0044In this project, researchers developed a proposal to extend the delivery of the recently developedGraduate Certificate in Transportation Planning at Texas A&M University (TAMU) to a wider audience viadistance education (online or ...
Texas Transportation Institute. University Transportation Center for Mobility   +2 more
core  

Retracted: Discussion on the Construction of Enterprise Internal Audit Informatization

open access: yesJournal of Advanced Transportation, 2023
Journal of Advanced Transportation
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Other title: Overview of the Kansas Department of Transportation Other title: Kansas Department of Transportation Overview Other title: KDOT Overview

open access: yes, 2011
application/pdf Title supplied by cataloger from Kansas Department of Transportation website. "February 3, 2011." Presentation to the Kansas Legislature, House Transportation Committee, by staff of the Kansas Department of Transportation.Presentation ...
Kansas. Department of Transportation.
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

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