Results 81 to 90 of about 2,542,719 (338)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Basic Transportation Economics [PDF]

open access: yes, 1972
Transportation economics is an integral part of all transportation activities. Refined, detailed, and careful economic analyses consider conduct-performance methodology and the specifications of production, cost and demand ...
Kneafsey, J. T.
core   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Retracted: Study on Abnormal Transmission of Date Frames Based on PT-CAN Bus

open access: yesJournal of Advanced Transportation, 2023
Journal of Advanced Transportation
doaj   +1 more source

Biofuels for Transportation [PDF]

open access: yes, 2006
The world is on the verge of an unprecedented increase in the production and use of biofuels. Rising oil prices, national security concerns, the desire to increase farm incomes, and a host of new and improved technologies are propelling many governments ...

core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Transportation decisions of small businesses in Soweto: Balancing responsiveness and efficiency

open access: yesJournal of Transport and Supply Chain Management, 2016
Background: The performance of small businesses makes an important contribution to the South African economy. Although the South African government implemented various initiatives for the development of small businesses in townships, the full advantage ...
Themari Eicker, Jacoba O. Cilliers
doaj   +1 more source

Expenditures on Public Transportation [PDF]

open access: yes, 1999
Public transportation expenditures consumed 6 percent of the average household\u27s transporation budget in 1997, divided between intracity and intercity travel (22 percent and 78 percent of total public transportation expenditures, respectively ...
Bureau of Labor Statistics
core   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

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