Results 91 to 100 of about 1,006,093 (289)

Three orbital transfer vehicles [PDF]

open access: yes
Aerospace engineering students at the Virginia Polytechnic Institute and State University undertook three design projects under the sponsorship of the NASA/USRA Advanced Space Design Program.

core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Integrating Hybrid Energy Solutions into Expressway Infrastructure

open access: yesEnergies
To explore the feasibility of renewable hybrid energy systems for expressway infrastructure, this study proposes a scenario-based design methodology integrating solar, wind, and hydropower resources within the expressway corridor.
Muqing Yao   +6 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

What a Systematic Literature Review Tells Us About Transportation Engineering Education [PDF]

open access: gold, 2015
Rhonda Young   +3 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

ECONOMIC PROSPECTS FOR SMALL-SCALE FUEL ALCOHOL PRODUCTION [PDF]

open access: yes
Small-scale alcohol plants will have difficulty in supplying fuel that is competitive in cost with petroleum-based fuels. This is based upon economic findings form interdisciplinary research with a pilot fuel alcohol plant.
Dobbs, Thomas L.   +2 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Design of a CO2 laser power control system for a Spacelab microgravity experiment [PDF]

open access: yes
The surface tension driven convection experiment (STDCE) is a Space Transportation System flight experiment manifested to fly aboard the USML-1 Spacelab mission.
Eichenberg, Dennis J., Wenzler, Carl J.
core   +1 more source

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