Results 71 to 80 of about 3,287,426 (295)

A Flipped Classroom Approach to Teaching Transportation Engineering

, 2016
The flipped classroom approach has gained increasing popularity in higher education, particularly in STEM fields. In flipped learning, part or all of direct instruction is delivered through online videos and other media, and the class time is used for ...
A. Karabulut-Ilgu, Suhan Yao, P. Savolainen, C. Jahren   +3 more
semanticscholar   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Flight Schedule Optimization Considering Fine-Grained Configuration of Slot Coordination Parameters

Aerospace
In response to the rapid growth of air passenger and cargo transportation services and the sharp increase in congestion at various airports, it is necessary to optimize the allocation of flight schedules.
Jingyi Yu, Minghua Hu, Zheng Zhao, Bin Jiang   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Quantifying volatility characteristics of passenger flow in metro stations based on rolling-window

Journal of Highway and Transportation Research and Development
Understanding the characteristics of passenger flows within a metro network is essential to enhance the operational efficiency and safety of urban rail transit system.
Zhao Liu, Dan Ning, Wenming Rao, Meng Jia   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Symmetry in Civil Transportation Engineering

Symmetry
Symmetrical structures, such as tunnels, diaphragm walls, and blasting charge structures, are becoming increasingly prevalent in civil transportation engineering [...]
Yao Bai, Renliang Shan
openaire   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Passenger evacuation for ultra-long escalator malfunctions under high passenger flow in multi-level ultra-deep metro interchange hubs

Shenzhen Daxue xuebao. Ligong ban
In cities with limited existing space, the construction of new metro stations increasingly focuses on efficient and intensive land use, with station designs trending towards deeper and more complex structures.
LIAO Wenkang, LOU Xiaolei, HU Mingwei, YANG Wenjie   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source