Results 71 to 80 of about 1,038,949 (301)

Some Applications of Polynomial Optimization in Operations Research and Real-Time Decision Making [PDF]

, 2015
We demonstrate applications of algebraic techniques that optimize and certify polynomial inequalities to problems of interest in the operations research and transportation engineering communities.
Ahmadi, Amir Ali, Majumdar, Anirudha
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Evaluation Method for Nighttime Visual Space Improvement on Mountain Roads

Zhongwai Gonglu
To address issues such as poor visual guidance, narrow field of view, and short sight distance during nighttime driving on mountain roads, this study proposed a visual space enhancement evaluation method applicable to mountainous roads at night.
ZHAO Yan, CHEN Yanli, CHEN Jiale
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Demand responsive transit scheduling method considering passenger travel choice

Shenzhen Daxue xuebao. Ligong ban
Demand responsive transit service faces the challenge of maintaining operating profits while complying with passenger preferences. To address this, a multinomial logit model was established to describe passenger travel choice behaviors, and a service ...
SUN Jie, JIN Wenzhou, ZHANG Yong
doaj   +1 more source

Engaging Undergraduate Students in Transportation Studies through Simulating Transportation for Realistic Engineering Education and Training (STREET) [PDF]

The practice of transportation engineering and planning has evolved substantially over the past several decades. A new paradigm for transportation engineering education is required to better engage students and deliver knowledge.
Chen-Fu Liao, David Levinson, Henry Liu
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Safety control of monotone systems with bounded uncertainties [PDF]

, 2016
Monotone systems are prevalent in models of engineering applications such as transportation and biological networks. In this paper, we investigate the problem of finding a control strategy for a discrete time positive monotone system with bounded ...
Belta, Calin, Sadraddini, Sadra
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Digital Dissemination Platform of Transportation Engineering Education Materials Founded in Adoption Research [PDF]

, 2014
INE/AUTC 14 ...
Perkins, Robert A.
core