Results 71 to 80 of about 160,704 (261)
Symmetry in Civil Transportation Engineering
SymmetrySymmetrical structures, such as tunnels, diaphragm walls, and blasting charge structures, are becoming increasingly prevalent in civil transportation engineering [...]
Yao Bai, Renliang Shan
openaire +1 more source
Formatting a questionnaire for the quality control of river bank roads
Open EngineeringThe quality control of road implementation on the rim and the strengthening of river edges to prevent road collapses need to be studied and developed continuously.
Salem Zahraa Amad, Ibraheem Asma Thamir
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Vehicle scheduling optimization for demand responsive transit with flexible stops
Shenzhen Daxue xuebao. Ligong banFlexible stops demand responsive transit is a public transportation mode that combines fixed service stops with the ability for passengers to book at flexible stops.
SHEN Zikang, JIN Wenzhou, ZHENG Yajing
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Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
FEBS Letters, EarlyView.Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Demand distribution analysis and layout optimization for flex-route transit
Shenzhen Daxue xuebao. Ligong banThis work investigates the random distribution analysis of demand and layout adjustment for flex-route transit (FRT) based on historical data. Focusing on an FRT line with operational origin destination (OD) data, the study addresses demand uncertainty ...
GAN Junjie, PANG Mingbao, JIN Mingyue
doaj +1 more source