Results 61 to 70 of about 5,497,503 (307)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Transportation Engineering Course [PDF]

DTRT07-G-0056The goal of this work was to develop activity-based learning materials for the introductory transportation engineering coursewith the purpose of increasing student understanding and concept retention.
National Institute for Advanced Transportation Technology (NIATT) (U.S.), Kyte, Michael, Tribelhorn, Maria   +2 more
core  

Finding Transportation Statistics

National Transportation Library (NTL) guide provides website links to resources related to the transportation industry. Includes statistics resources for general, multimodal, economic, highway, transit/rail, aviation and maritime ...
United States. Department of Transportation. National Transportation Library
core   +1 more source

Flight Schedule Optimization Considering Fine-Grained Configuration of Slot Coordination Parameters

Aerospace
In response to the rapid growth of air passenger and cargo transportation services and the sharp increase in congestion at various airports, it is necessary to optimize the allocation of flight schedules.
Jingyi Yu, Minghua Hu, Zheng Zhao, Bin Jiang   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Development of a special topics course on intelligent transportation systems for the Zachry Department of Civil Engineering of Texas A&M University. [PDF]

DTRT06-G-0044With Intelligent Transportation Systems (ITS), engineers and system integrators blend emergingdetection/surveillance, communications, and computer technologies with transportation management andcontrol concepts to improve the safety and ...
Texas Transportation Institute. University Transportation Center for Mobility, Balke, Kevin N., Brydia, Robert E.   +2 more
core  

Quantifying volatility characteristics of passenger flow in metro stations based on rolling-window

Journal of Highway and Transportation Research and Development
Understanding the characteristics of passenger flows within a metro network is essential to enhance the operational efficiency and safety of urban rail transit system.
Zhao Liu, Dan Ning, Wenming Rao, Meng Jia   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Engaging Undergraduate Students in Transportation Studies through Simulating Transportation for Realistic Engineering Education and Training (STREET) [PDF]

The practice of transportation engineering and planning has evolved substantially over the past several decades. A new paradigm for transportation engineering education is required to better engage students and deliver knowledge.
Chen-Fu Liao, Henry Liu, David Levinson
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source