Results 161 to 170 of about 155,579 (290)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Psychological determinants of transport mode choice: A comprehensive dataset from Pabna Municipality, Bangladesh. [PDF]

Data Brief
Hossain MN, Aman N, Sabbir MRI, Haque MR, Islam MT.   +4 more
europepmc   +1 more source

Engineering and Transport [PDF]

Nature, 1937
openaire   +1 more source

Context Awareness and Model Driven Engineering: A Multi-Level Approach for the Development of Interactive Applications in Public Transportation

, 2008
Arnaud Brossard, Mourad Abed, Christophe Kolski   +2 more
openalex   +1 more source

Dynamic Calculation and Analysis of the Fee Rate for Safe and Civilized Construction in Railway Transportation Engineering Based on PSO-SVM [PDF]

Yongtao Hu, Hao Ma, Liuya Huang
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Maximising environmental savings from silicon photovoltaics manufacturing to 2035. [PDF]

Nat Commun
Willis BL, Rigby OM, Pain SL, Grant NE, Murphy JD, Bonilla RS, Beattie NS.   +6 more
europepmc   +1 more source

Environmental sensitive road planning and transportation techniques in forest engineering

, 2015
H. Hulusi Acar
openalex   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Mapping neighbourhood-level drivers of type 2 diabetes for precision public health using predictive and causal machine learning. [PDF]

Sci Rep
Noaeen M, Rostami A, Ghanem I, Saarela O, Keshavjee K, Brook JR, Shakeri Z.   +6 more
europepmc   +1 more source