Results 91 to 100 of about 384,570 (251)

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +8 more
wiley   +1 more source

Electric Aircraft and the Environment: A Literature Review [PDF]

, 2018
Historically, the integration of social need, environmental impact, and technological advancement has been a challenging balancing act for growing cities and metropoles.
Sou, Uyen T.
core   +1 more source

Does Long‐Term Lower Extremity Strength Training in Adults With Knee Osteoarthritis and Varus Alignment Reduce Knee Joint Loading During Gait?

Arthritis Care &Research, EarlyView.
Objective We examined whether 18 months of strength training in individuals with knee varus alignment and medial tibiofemoral osteoarthritis (OA) reduced knee joint loads during walking compared to an attention control group. Methods This study was a secondary analysis of a randomized clinical trial that compared the effects of strength training to a ...
Stephen P. Messier, Matthew N. Vigliotti, Paige E. Rice, Brian Pietrosimone, Shannon L. Mihalko, Edward H. Ip, Richard F. Loeser, David J. Hunter, Ali Guermazi, Ryan Hill, Santiago Saldana, Kim L. Bennell, Paul DeVita   +12 more
wiley   +1 more source

Long-term exposure to transportation noise and its association with adiposity markers and development of obesity

Environment International, 2018
The contribution of different transportation noise sources to metabolic disorders such as obesity remains understudied. We evaluated the associations of long-term exposure to road, railway and aircraft noise with measures of obesity and its subphenotypes
Maria Foraster, Ikenna C. Eze, Danielle Vienneau, Emmanuel Schaffner, Ayoung Jeong, Harris Héritier, Franziska Rudzik, Laurie Thiesse, Reto Pieren, Mark Brink, Christian Cajochen, Jean-Marc Wunderli, Martin Röösli, Nicole Probst-Hensch   +13 more
doaj   +1 more source

A user-oriented and computerized model for estimating vehicle ride quality [PDF]

A simplified empirical model and computer program for estimating passenger ride comfort within air and surface transportation systems are described.
Barker, L. M., Leatherwood, J. D.
core   +1 more source

Multi-Output Gaussian Processes for Crowdsourced Traffic Data Imputation

, 2019
Traffic speed data imputation is a fundamental challenge for data-driven transport analysis. In recent years, with the ubiquity of GPS-enabled devices and the widespread use of crowdsourcing alternatives for the collection of traffic data, transportation
Henrickson, Kristian, Pereira, Francisco C., Rodrigues, Filipe   +2 more
core   +1 more source

A Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller

International Journal of Adaptive Control and Signal Processing, EarlyView.
Block Diagram of the Robust Adaptive One‐Sample‐Ahead Preview Super‐Twisting Sliding Mode Controller. ABSTRACT This article introduces a discrete‐time robust adaptive one‐sample‐ahead preview super‐twisting sliding mode controller. A stability analysis of the controller by Lyapunov criteria is developed to demonstrate its robustness in handling both ...
Guilherme Vieira Hollweg, Paulo Jefferson Dias de Oliveira Evald, Shivam Chaturvedi, Hilton Abilio Gründling, Rodrigo Varella Tambara, Wencong Su   +5 more
wiley   +1 more source

Time-Frequency Analysis of Horizontal Vibration for Vehicle-Track System Based on Hilbert-Huang Transform

Advances in Mechanical Engineering, 2013
Relationship between track alignment irregularity and car body horizontal vibration acceleration is analyzed by using Hilbert-Huang Transform (HHT). Actual measured alignment irregularity and car body horizontal vibration acceleration are decomposed by ...
Zaiwei Li, Songliang Lian, Yuelei He
doaj   +1 more source

Realizing modeling and mapping tools to study the upsurge of noise pollution as a result of open-cast mining and transportation activities

Noise and Health, 2018
Introduction: In open-cast mines, noise pollution has become a serious concern due to the extreme use of heavy earth moving machinery (HEMM). Materials and Methods: This study is focused to measure and assess the effects of the existing noise levels of ...
Satish K Lokhande, Mohindra C Jain, Satyajeet A Dhawale, Rakesh Gautam, Ghanshyam L Bodhe   +4 more
doaj   +1 more source