Results 71 to 80 of about 2,526,065 (280)
Urban Rail TransitWith the rapid construction of rail transportation infrastructure, vibration issues caused by wheel–rail interactions during train operation have become a significant concern.
Fangqiu Sun +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Journal of Physics: Conference Series, 2023 Abstract The research examines the sources of rail transport noise. Noise depends on the type of locomotives, warning signals, maintenance, and construction equipment. The wheel–to–rail contact of the rolling stock and the locomotives’ propulsion systems are the noise sources.
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Aerospace, 2021 Air traffic contributes to anthropogenic global warming by about 5% due to CO2 emissions and non-CO2 effects, which are primarily caused by the emission of NOx and water vapor as well as the formation of contrails.
Benjamin Lührs +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Fluctuating noise drives Brownian transport [PDF]
Journal of The Royal Society Interface, 2012 The transport properties of Brownian ratchet were studied in the presence of stochastic intensity noise in both overdamped and underdamped regimes. In the overdamped case, an analytical solution using the matrix-continued fraction method revealed the existence of a maximum current when the noise intensity fluctuates on intermediate ...
Hasegawa, Yoshihiko, Arita, Masanori
openaire +3 more sources
Scandinavian Journal of Work, Environment & Health, 2017 OBJECTIVES: National quantifications of the health burden related to traffic noise are still rare. In this study, we use disability-adjusted life-years (DALY) measure to assess the burden of disease from road traffic and railway noise in Sweden. METHODS:
Charlotta Eriksson +2 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source