Results 51 to 60 of about 44,546 (307)

Burden of disease from road traffic and railway noise – a quantification of healthy life years lost in Sweden

Scandinavian Journal of Work, Environment & Health, 2017
OBJECTIVES: National quantifications of the health burden related to traffic noise are still rare. In this study, we use disability-adjusted life-years (DALY) measure to assess the burden of disease from road traffic and railway noise in Sweden. METHODS:
Charlotta Eriksson, Theo Bodin, Jenny Selander   +2 more
doaj   +1 more source

Noise-induced transport at zero temperature [PDF]

Journal of Physics A: Mathematical and General, 1998
We consider a particle in the over-damped regime at zero temperature under the influence of a sawtooth potential and of a noisy force, which is correlated in time. A current occurs, even if the mean of the noisy force vanishes. We calculate the stationary probability distribution and the stationary current.
Kohler, Heiner, Mielke, Andreas
openaire   +3 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Noise Assessment and Abatement in Rapid Transit Systems: Report on the MBTA Pilot Study [PDF]

A methodology is described for assessing the noise climate and for selecting the combination of abatement techniques which reduces the existing noise to user specified levels for minimum cost.
Apgar, E., Kurzweil, Leonard G., John A. Volpe National Transportation Systems Center (U.S.), Lotz, G.   +3 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Relationship Analysis between Vegetation and Traffic Noise Pollution: A Case Study Lahore, Pakistan

International Journal of Economic and Environment Geology, 2021
The problem of exposure to traffic noise pollution is rapidly increasing day by day and is closely associated with the rapid industrialization and urbanization process taking place over the glob (Margaritis and Kang, 2016). Nowadays, more than 54% of the
Sahar Zia , Saba Yaqoob , Ayesha Hanif , Muhammad Nasar-u- Minallah , A. Aslam   +4 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Assessment of Noise from Transportation Systems in Ilorin, Nigeria

Nigerian Journal of Technological Development, 2019
Noise from transportation systems is unavoidable in urban areas and can be harmful to human health. The noise generated by selected transportations systems in Ilorin, an urban area in central Nigeria, was studied by direct measurements and the use of ...
S. O. Bilewu, A. W. Salami, A. M. Ayanshola, I. T. Yusuf   +3 more
doaj   +2 more sources

Transportation noise and the cardiometabolic risk

Atherosclerosis
Transportation noise is a widespread and often underestimated environmental pollutant, posing a substantial health risk particularly in urban areas. In contrast to air pollution, the health effects of noise pollution are less extensively documented. Defined as an unwanted and/or harmful sound, noise pollution affects over 20 % of the European Union (EU)
Thomas Münzel, Marin Kuntic, Andreas Daiber, Mette Sørensen   +3 more
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source