Results 51 to 60 of about 1,885,759 (302)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Climate Impact Mitigation Potential of European Air Traffic in a Weather Situation with Strong Contrail Formation

open access: yesAerospace, 2021
Air traffic contributes to anthropogenic global warming by about 5% due to CO2 emissions and non-CO2 effects, which are primarily caused by the emission of NOx and water vapor as well as the formation of contrails.
Benjamin Lührs   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Burden of disease from road traffic and railway noise – a quantification of healthy life years lost in Sweden

open access: yesScandinavian Journal of Work, Environment & Health, 2017
OBJECTIVES: National quantifications of the health burden related to traffic noise are still rare. In this study, we use disability-adjusted life-years (DALY) measure to assess the burden of disease from road traffic and railway noise in Sweden. METHODS:
Charlotta Eriksson   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Assessment of Noise from Transportation Systems in Ilorin, Nigeria

open access: yesNigerian Journal of Technological Development, 2019
Noise from transportation systems is unavoidable in urban areas and can be harmful to human health. The noise generated by selected transportations systems in Ilorin, an urban area in central Nigeria, was studied by direct measurements and the use of ...
S. O. Bilewu   +3 more
doaj   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Environmental Noise Exposure and the Risk of Sleep Disturbance: A Systematic Review and Meta-Analysis

open access: yesNoise and Health
Objective: To systematically evaluate the association between different types of environmental noise, particularly traffic noise, and sleep disturbances; to quantify the effect size and to explore key factors contributing to heterogeneity, thereby ...
Zitong Li
doaj   +1 more source

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