Results 81 to 90 of about 487,951 (354)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Social and emotional problems in the rehabilitation of cancer patients: a study of 14 patients age 60-75 with cancer of the cervix. [PDF]

, 1956
Thesis (M.S.)--Boston ...
McNulty, Eileen M
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Campus Update: May 1991 v. 3, no. 5 [PDF]

, 1991
Monthly newsletter of the BU Medical ...
Boston University Medical Center, O'Brien, Jennifer C.   +1 more
core   +1 more source

Improving Laws and Legal Authorities for Obesity Prevention and Control [PDF]

, 2009
This is the second paper in a two part series on the laws and legal authorities for obesity prevention and control. In this paper, the authors present the applicable laws and legal authorities that public health professionals and lawyers can consider ...
Gostin, Lawrence O., Pomeranz, Jennifer L.   +1 more
core   +3 more sources

Outcomes of Urgent Interhospital Transportation for Extracorporeal Membrane Oxygenation Patients

Journal of Chest Surgery, 2022
Background: Extracorporeal membrane oxygenation (ECMO) can be used in patients with refractory cardiogenic shock or respiratory failure. In South Korea, the need for transporting ECMO patients is increasing.
Jun Tae Yang, Hyoung Soo Kim, Kun Il Kim, Ho Hyun Ko, Jung Hyun Lim, Hong Kyu Lee, Yong Joon Ra   +6 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Suburban Poverty and the Health Care Safety Net [PDF]

, 2009
Examines trends in the number of suburban poor, their access to health care, and efforts to improve safety-net services in the suburbs of five cities.
Johanna R. Lauer, Laurie E. Felland, Peter J. Cunningham   +2 more
core  

Adult trauma centers in Poland: where do we stand?

International Journal of Emergency Medicine
Background A trauma system based on trauma centers was established in Poland only at the beginning of the second decade of the century. The aim of this study was to quantitatively and comparatively assess the functioning of the trauma system in Poland ...
Tomasz Sanak, Jakub Nożewski, Mateusz Putowski, Aleksandra Załustowicz, Adam Burakowski, Klimek Józefowicz, Sylweriusz Kosiński   +6 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source