Results 151 to 160 of about 552,532 (299)

Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions [PDF]

, 2019
Hee Eun Kang, Melina M. Malinen, Chitra Saran, Paavo Honkakoski, Kim L. R. Brouwer   +4 more
openalex   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Contribution of organic anion transporting polypeptides to bile acid uptake in the Caco-2 cell monolayer and gastrointestinal tract. [PDF]

J Biol Chem
Kurobe-Takashima Y, Yanagisawa K, Saito Y, Miyawaki R, Misaka T, Mizoi J, Miyauchi E, Sasaki N, Ogihara T, Kobayashi S.   +9 more
europepmc   +1 more source

The effects of mutated cationic amino acid transporter y+LAT1 at the cellular and systemic level

, 2015
Maaria Tringham
openalex   +1 more source

Astrocytic modulation of population encoding in mouse visual cortex via GABA transporter 3 revealed by multiplexed CRISPR/Cas9 gene editing

Ji Ho Park, Grayson O. Sipe, Xin Tang, Prachi Ojha, Giselle Fernandes, Yi Ning Leow, Caroline Zhang, Yuma Osako, Arundhati Natesan, Gabrielle T Drummond, Rudolf Jaenisch, Mriganka Sur   +11 more
openalex   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Ileal bile acid transporter inhibitors for chronic constipation in the elderly. [PDF]

World J Gastrointest Pharmacol Ther
Aneesh PSR, Vaithiyam V, Reddy RT, Dalal A, Sachdeva S.   +4 more
europepmc   +1 more source

Study of the regulation of a zinc transporter in Leishmania infantum

, 2013
Ana Sofia Ferreira Ramos
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Transporters, an important but poorly studied area of Toxoplasma gondii. [PDF]

Parasit Vectors
Wang L, Jing Y, Yang J, Yang X, Qian J, Fang R, Jian F, Zhang L, Li S.   +8 more
europepmc   +1 more source